(2,2-dimethyl-3,4-dihydro-2H-chromen-4-yl)amine
2,2-Dimethyl-chroman-4-ylamine
CAS: 220634-41-3
Molecular Formula: C11H15NO
(2,2-dimethyl-3,4-dihydro-2H-chromen-4-yl)amine - Names and Identifiers
(2,2-dimethyl-3,4-dihydro-2H-chromen-4-yl)amine - Physico-chemical Properties
| Molecular Formula | C11H15NO |
| Molar Mass | 177.24 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD08687615 |
(2,2-dimethyl-3,4-dihydro-2H-chromen-4-yl)amine - Introduction
2,2-Dimethy1-chroman-4-ylamine is an organic compound with the chemical formula C13H17NO. It is a colorless to pale yellow liquid with a benzene hydrocarbon aroma. The following is a detailed description of the nature, use, preparation and safety information of 2,2-Dimethyl-chroman-4-ylamine:
Nature:
-Appearance: Colorless to light yellow liquid
-Molecular weight: 203.27g/mol
-Melting point:-7.5 ℃(25 ℃)
-Boiling point: 150 ℃(3.6 mmHg)
-Density: Approximately 0.987 g/mL(25°C)
-Solubility: Soluble in most organic solvents, such as ethanol, ether and ketone.
Use:
- 2,2-Dimethyl-chroman-4-ylamine can be used as a reagent and intermediate in organic synthesis.
-It can be used to synthesize organic compounds such as drugs, dyes and functional molecules.
-In the drug development process, 2,2-Dimethyl-chroman-4-ylamine is often used to synthesize biologically active compounds.
Preparation Method:
2,2-Dimethyl-chroman-4-ylamine has a variety of synthetic methods. A common preparation method is synthesized by the hydrogenation reaction of the benzene ring, the specific steps are as follows:
1. In a reaction vessel, 2,2-dimethyl-3,4-dihydro -2H-1-benzopyran-4-one and an amination reagent (such as ammonia, methylamine, etc.) are added to the reactant.
2. Under the protection of inert gas, a reducing agent (such as sodium hydride, lithium aluminum hydride, etc.) is added, and the reaction solution is stirred for reaction.
3. After the reaction is completed, the pure product of 2,2-Dimethyl-chroman-4-ylamine is obtained by distillation or other separation and purification techniques.
Safety Information:
- 2,2-Dimethyl-chroman-4-ylamine is irritating to eyes and skin, and should be protected when using it.
-If ingested or inhaled, seek medical attention immediately.
-During storage and handling, general laboratory safety practices should be followed to avoid contact with skin, eyes and other sensitive areas.
-It is recommended to use in a well-ventilated place to avoid inhaling gas or steam.
-It is recommended to wear appropriate personal protective equipment, such as laboratory gloves, safety goggles, protective clothing, etc.
Nature:
-Appearance: Colorless to light yellow liquid
-Molecular weight: 203.27g/mol
-Melting point:-7.5 ℃(25 ℃)
-Boiling point: 150 ℃(3.6 mmHg)
-Density: Approximately 0.987 g/mL(25°C)
-Solubility: Soluble in most organic solvents, such as ethanol, ether and ketone.
Use:
- 2,2-Dimethyl-chroman-4-ylamine can be used as a reagent and intermediate in organic synthesis.
-It can be used to synthesize organic compounds such as drugs, dyes and functional molecules.
-In the drug development process, 2,2-Dimethyl-chroman-4-ylamine is often used to synthesize biologically active compounds.
Preparation Method:
2,2-Dimethyl-chroman-4-ylamine has a variety of synthetic methods. A common preparation method is synthesized by the hydrogenation reaction of the benzene ring, the specific steps are as follows:
1. In a reaction vessel, 2,2-dimethyl-3,4-dihydro -2H-1-benzopyran-4-one and an amination reagent (such as ammonia, methylamine, etc.) are added to the reactant.
2. Under the protection of inert gas, a reducing agent (such as sodium hydride, lithium aluminum hydride, etc.) is added, and the reaction solution is stirred for reaction.
3. After the reaction is completed, the pure product of 2,2-Dimethyl-chroman-4-ylamine is obtained by distillation or other separation and purification techniques.
Safety Information:
- 2,2-Dimethyl-chroman-4-ylamine is irritating to eyes and skin, and should be protected when using it.
-If ingested or inhaled, seek medical attention immediately.
-During storage and handling, general laboratory safety practices should be followed to avoid contact with skin, eyes and other sensitive areas.
-It is recommended to use in a well-ventilated place to avoid inhaling gas or steam.
-It is recommended to wear appropriate personal protective equipment, such as laboratory gloves, safety goggles, protective clothing, etc.
Last Update：2024-04-09 15:18:09
