(2-Fluoro-4-iodopyridin-3-yl)methanol

(2-Fluoro-4-iodopyridin-3-yl)methanol - Names and Identifiers

Name	2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE
Synonyms	2-Fluoro-4-iodo-3-pyridinemethanol 3-Pyridinemethanol,2-fluoro-4-iodo- 3-Pyridinemethanol, 2-fluoro-4-iodo- (2-Fluoro-4-iodopyridin-3-yl)methanol (2-Fluoro-4-iodopyridin-3-yl)Methanol 2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE
CAS	171366-19-1
InChI	InChI=1/C6H5FINO/c7-6-4(3-10)5(8)1-2-9-6/h1-2,10H,3H2

(2-Fluoro-4-iodopyridin-3-yl)methanol - Physico-chemical Properties

Molecular Formula	C6H5FINO
Molar Mass	253.01
Density	2.061
Boling Point	330.4±37.0 °C(Predicted)
Flash Point	153.6°C
Vapor Presure	6.68E-05mmHg at 25°C
pKa	12.27±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.63

(2-Fluoro-4-iodopyridin-3-yl)methanol - Introduction

2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE, also known as FHI, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Properties: 2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE is a colorless or slightly yellow solid. It has the molecular formula C6H5FINO and a molecular weight of 261.02G/mole. It has a melting point of 60-63°C and a boiling point of 238-240°C. This compound is soluble in ethanol and dichloromethane.

Purpose: 2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE is often used as an intermediate in organic synthesis. It can be used to prepare complex organic compounds with biological activity, such as pesticides, drugs and ligands. In addition, it can also be used as a building block of heterocyclic ketones and an important intermediate in the synthesis of photovoltaic materials.

Preparation Method: The preparation of 2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE is usually achieved by a chemical synthesis method. One commonly used method is the reaction of 2-fluoro-3-hydroxymethylpyridine under basic conditions using iodine. In this reaction, 2-fluoro-3-hydroxymethylpyridine is used as a substrate, potassium hydroxide or sodium hydroxide is used as a base catalyst, and iodine is used as a reactant.

Safety information: 2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE is generally relatively safe under normal operating conditions. However, it is an organic compound, so appropriate protective measures need to be taken. Wear appropriate protective gloves, goggles and lab coats when operating. Avoid contact with skin, eyes and other mucous membranes. In addition, it should be operated in a well-ventilated area to avoid inhaling its gas, steam or dust. If inhalation, ingestion or contact with skin discomfort, should immediately seek medical advice. When stored, it should be kept in a sealed container, away from fire and oxidizing agents.

Last Update：2024-04-09 20:52:54