(2-bromo-6-fluorophenyl)-triethylsilane - Names and Identifiers
(2-bromo-6-fluorophenyl)-triethylsilane - Physico-chemical Properties
(2-bromo-6-fluorophenyl)-triethylsilane - Introduction
(2-bromo-6-fluorophenyl)-triethylsilane is an organosilicon compound with the chemical formula C14H20BrFSi.
Nature:
-Appearance: colorless liquid
-Melting point: below -20 ℃
-Boiling Point: 218-220 ℃
-Density: 1.11g/cm³
-Solubility: Soluble in non-polar organic solvents such as benzene and ether, insoluble in water.
Use:
(2-bromo-6-fluorophenyl)-triethylsilane can be used as a reagent and intermediate in organic synthesis, and has the following main applications:
-as a source of silicon to activate olefins, to participate in the synthesis reaction of silicon olefins.
-Used as an important intermediate in the synthesis of drugs and pesticides.
-Participate in organometallic catalyzed reactions, such as building carbon-silicon bonds.
Method:
The preparation of (2-bromo-6-fluorophenyl)-triethylsilane can be carried out by the following method:
-React 2-bromo-6-fluorobenzene and triethylchlorosilane in a reaction solvent, such as chloroalkanes (such as toluene or gasoline).
-2-bromo-6-fluorobenzene is added with sodium triethyl silicide in dichloromethane to produce the product after the reaction is carried out.
Safety Information:
(2-bromo-6-fluorophenyl)-triethylsilane has limited safety and requires appropriate operation measures for operation and storage. Here are some safety considerations:
-Avoid skin and eye contact when touching. If contact occurs, flush immediately with plenty of water and seek medical help.
-Wear protective gloves, goggles and protective clothing to ensure a well-ventilated operating environment.
-Avoid breathing its vapors or dust. Please make sure to operate in a well-ventilated place when using.
-It is strictly forbidden to mix this compound with strong oxidants or strong acids to avoid dangerous reactions.
-When storing, keep it in a light-proof, sealed container, away from fire and high temperature.
This information is for reference only. Please read the relevant chemical safety information carefully when using or operating.
Last Update：2024-04-09 15:18:03