(2-氟-6-甲基吡啶3-基)硼酸

(2-氟-6-甲基吡啶3-基)硼酸 - Names and Identifiers

Name	2-Fluoro-6-methylpyridine-3-boronic acid
Synonyms	2-Fluoro-6-picoline-3-boronic acid 2-Fluoro-6-methylpyridin-3-ylboronicaci 2-Fluoro-6-methylpyridine-3-boronic acid (2-fluoro-6-methylpyridin-3-yl)boronic acid B-(2-fluoro-6-methyl-3-pyridinyl)-Boronic acid Boronic acid, B-(2-fluoro-6-methyl-3-pyridinyl)-
CAS	906744-85-2
InChI	InChI=1/C6H7BFNO2/c1-4-2-3-5(7(10)11)6(8)9-4/h2-3,10-11H,1H3

(2-氟-6-甲基吡啶3-基)硼酸 - Physico-chemical Properties

Molecular Formula	C6H7BFNO2
Molar Mass	154.93
Density	1.28±0.1 g/cm3(Predicted)
Boling Point	308.4±52.0 °C(Predicted)
Flash Point	140.3°C
Vapor Presure	0.000296mmHg at 25°C
pKa	6.94±0.58(Predicted)
Storage Condition	2-8°C
Refractive Index	1.504

(2-氟-6-甲基吡啶3-基)硼酸 - Introduction

Acid is an organic compound with the chemical formula C6H8BFNO2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: White crystalline powder
-Solubility: Soluble in solvents such as water, ethanol and chloroform
-Melting point: approximately 110-113 degrees Celsius
-Molecular weight: 148.94g/mol

Use:
-acid is an important organic synthesis intermediate, commonly used in organic synthesis chemical reactions.
-It can be used as a ligand in organolithium compounds and metal organic catalysts to catalyze coupling reactions, such as Suzuki coupling reactions.
-It can also be used as an important raw material for drug development and pesticide synthesis.

Method:
The preparation method of-Cr acid can be obtained by the reaction of benzyl compound and sodium azide, and then reduced by sodium borohydride.

Safety Information:
-the acid is generally safe under normal use conditions, but the following matters still need to be paid attention:
-It may cause irritation to the eyes, skin and respiratory tract, please pay attention to the use of personal protective measures, such as wearing appropriate protective gloves and safety glasses.
-Avoid inhaling the dust or gas of the compound. Please operate in a well-ventilated place.
-When storing and handling, please keep it away from fire and oxidant to avoid fire and explosion.
-For detailed safety information and operating methods, please refer to the safety data sheet (SDS) of the relevant chemical.

Last Update：2024-04-09 15:18:00