(25R)-3β-(2-O-α-L-Rhamnopyranosyl-3-O-β-D-glucopyranosyl-β-D-glucopyranosyloxy)spirosta-5-ene
Gracillin
CAS: 19083-00-2
Molecular Formula: C45H72O17
(25R)-3β-(2-O-α-L-Rhamnopyranosyl-3-O-β-D-glucopyranosyl-β-D-glucopyranosyloxy)spirosta-5-ene - Names and Identifiers
(25R)-3β-(2-O-α-L-Rhamnopyranosyl-3-O-β-D-glucopyranosyl-β-D-glucopyranosyloxy)spirosta-5-ene - Physico-chemical Properties
| Molecular Formula | C45H72O17 |
| Molar Mass | 885.04 |
| Density | 1.42 |
| Melting Point | 290-293℃ (DEC.) |
| Specific Rotation(α) | -88 (Py) |
| Solubility | DMSO:100 mg/mL (112.98 mM) |
| Appearance | Colorless needle crystal |
| pKa | 12.78±0.70(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Sensitive | Easily absorbing moisture |
| MDL | MFCD28978176 |
| Physical and Chemical Properties | White powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the rhizome of Dioscorea zingiberensis and Dioscorea zingiberensis. |
(25R)-3β-(2-O-α-L-Rhamnopyranosyl-3-O-β-D-glucopyranosyl-β-D-glucopyranosyloxy)spirosta-5-ene - Risk and Safety
| HS Code | 29329990 |
(25R)-3β-(2-O-α-L-Rhamnopyranosyl-3-O-β-D-glucopyranosyl-β-D-glucopyranosyloxy)spirosta-5-ene - Reference
| Reference Show more | 1. Li Li, Shuai Zhao, Meng Li, Yanmin Li, et al. Preparation, characterization and in vitro hemolysis analysis of the extracts of the flower of the leaf and the root of the root of the black and the root of the root [J]. Chinese Journal of Experimental prescriptions 2017(21):7-12. 2. Li Li, Shuai Zhao, Meng Li, Yanmin Li, et al. Study on analgesic and anti-inflammatory effects of extracts from rhizomes and aerial parts of pigeonba [J]. Natural product research and development 2018 030(005):832-839. 3. Gao Yan, Li Dewang, et al. Research on UPLC characteristic Atlas of Paris polyphylla in Yunnan [J]. China Food and Drug Administration No. 2019 No.188(09):40-46. 4. Juboya Li Yanmin, Zhu Houda, fangyunge, Wang, Rui, Chen, er, Wu, Gao, Hui, Min, Wang, Zhi, min. On improving the quality standard of Chinese Pharmacopoeia (2020 edition). Chinese Journal of Experimental prescriptions, 2019, 25(19):93-101. 5. Sun Peng, Yin Haobo, Yao Jia. Content changes of saponins from Dioscorea nipponica Makino under continuous cropping obstacle [J]. Practical Medicine and clinic, 2016(3):339-342, a total of 4 pages. 6. Liu, Mengshun, et al. "Folding fan mode counter-current chromatography offers fast blind screening for drug discovery. Case study: Finding anti-enterovirus 71 agents from Anemarrhena asphodeloides." Journal of Chromatography A 1368 (2014): 116-124.https:// 7. [IF=4.759] Mengshun Liu et al."Folding fan mode counter-current chromatography offers fast blind screening for drug discovery. Case study: Finding anti-enterovirus 71 agents from Anemarrhena asphodeloides."J Chromatogr A. 2014 Nov;1368:116 8. [IF=4.242] Shun Zhou et al."Anthelmintic efficacy of 35 herbal medicines against a monogenean parasite, Gyrodactylus kobayashii, infecting goldfish (Carassius auratus)."Aquaculture. 2020 May;521:734992 9. [IF=3.935] Liangjun Guan et al."Influence of drying process on furostanoside and spirostanoside profiles of Paridis Rhizoma by combination of HPLC, UPLC and UPLC-QTOF-MS/MS analyses."J Pharmaceut Biomed. 2021 Apr;197:113932 10. [IF=2.289] Zhou Shun et al."Anthelmintic efficacy of natural saponins against Gyrodactylus kobayashii in goldfish (Carassius auratus) and their 3D-QSAR analysis."Parasitol Res. 2021 Mar;120(3):1143-1150 |
(25R)-3β-(2-O-α-L-Rhamnopyranosyl-3-O-β-D-glucopyranosyl-β-D-glucopyranosyloxy)spirosta-5-ene - Reference Information
| function | the compound in anti-tumor, antibacterial, killing parasites, hemolysis, hypolipidemic, anti-osteoporosis, anti-mutation and other aspects have a certain physiological activity. |
| uses | has anti-tumor, improve cardiovascular function, regulate immunity, anti-platelet aggregation, at the same time, it is also an important raw material for the synthesis of various steroid hormones. dioscin has Antiasthmatic effect. |
| biological activity | gracilin is a steroidal saponin extracted from the roots of plants with anti-tumor properties. |
Last Update：2024-04-09 21:01:54
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Product Name: Gracillin Visit Supplier Webpage Request for quotationCAS: 19083-00-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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