(2E)-1-(2-Chlorophenyl)-3-(4-hydroxyphenyl)-prop-2-en-1-one - Names and Identifiers
(2E)-1-(2-Chlorophenyl)-3-(4-hydroxyphenyl)-prop-2-en-1-one - Physico-chemical Properties
Molecular Formula | C12H14F3N
|
Molar Mass | 229.24 |
Storage Condition | 2-8℃ |
Sensitive | Irritant |
MDL | MFCD10703520 |
(2E)-1-(2-Chlorophenyl)-3-(4-hydroxyphenyl)-prop-2-en-1-one - Introduction
{1-[4-(Trifluoromethyl) phenyl]-cyclobutyl} methylamine is an organic compound whose structure contains a cyclobutyl group and a methylamine group. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: colorless liquid
-Solubility: Soluble in organic solvents such as alcohols, ethers and aromatic hydrocarbons
-Melting point: about -30 to -20 ℃
-Boiling point: about 160 to 170 ℃
-Density: about 1.2 to 1.3g/cm³
Use:
The compound is commonly used as a reagent and intermediate in organic synthesis, and has the following applications:
-Can be used to synthesize pharmaceutically active compounds
-Used as a polymer additive
-Used as a ligand in some catalysts
Preparation Method:
A common method of preparation is by the condensation reaction of chloropyrimidine cyclobutyl-{4-[(trifluoromethyl) phenyl]} compound and methylamine:
1. First, the chloropyrimidine cyclobutyl-{4-[(trifluoromethyl) phenyl]} compound and methylamine are heated and stirred in an organic solvent, usually by adding a base (such as triethylamine) catalyst.
2. At the reaction temperature, the reaction is carried out for several hours until the reaction is complete.
3. After the reaction is over, the product is separated and purified by distillation or other methods.
Safety Information:
Since this compound is widely used in laboratories and industry, it is necessary to pay attention to its safe operation:
-The compound may be irritating to the eyes, skin and respiratory system, so it is necessary to wear appropriate protective equipment such as gloves, glasses and protective clothing when handling.
-Keep away from fire and high temperature during operation, and avoid contact with sparks, open flames and high temperature surfaces.
-Should be operated in a well-ventilated place to avoid inhaling the vapor of the compound.
-During storage, the compound should be kept sealed in a cool, dry place, away from oxidants and fire sources.
It should be noted that due to the nature and wide range of use of the compound, the above information is for reference only, and the specific use and operating conditions should be adjusted according to the specific situation. When handling the compound, be sure to follow the appropriate safety procedures and measures.
Last Update:2024-04-09 21:01:54