Name | Naringenin chalcone |
Synonyms | C06561 ISOSALIPURPOL Naringein chalcone Naringenin chalcone NARINGENIN CHALCONE 2',4',6',4-TETRAHYDROXYCHALCONE 4,2',4',6'-Tetrahydroxychalcone NARINGENIN CHALCONE(cis and trans Mix)(RG) (2E)-3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-2-propen-1-one |
CAS | 73692-50-9 |
Molecular Formula | C15H12O5 |
Molar Mass | 272.25 |
Density | 1.483±0.06 g/cm3(Predicted) |
Melting Point | 173-174℃ |
Boling Point | 538.7±50.0 °C(Predicted) |
Solubility | DMSO:54 mg/mL (198.34 mM) |
Appearance | Powder |
pKa | 6.82±0.40(Predicted) |
Storage Condition | 2-8℃ |
MDL | MFCD00016762 |
Physical and Chemical Properties | Chemical properties are soluble in methanol, ethanol, DMSO and other organic solvents. |
Use | Uses for content determination/identification/pharmacological experiments, etc. |
Reference Show more | 1. Ding Ning, Haiyan, Wang Xiaohui, Tu Pengfei, Gao Bowen, Shi shupo. Cloning, identification and expression analysis of chalcone isomerase gene from Aquilaria Sinensis [J]. Chinese Journal of Pharmacy, 2021,56(02):630-638. 2. Tan, Si, et al. "Lycopenee, polyphenols and antioxant activities of three characteristic tomato cultivars subject to two drinking methods." Food Chemistry 338 (2021): 128062.https://doi.org/10.1016/j.foodchem.2020.128062 3. [IF = 5.279] Ying Ying Wei et al. "Hot Air Treatment." J Agr Food Chem. 2017;65(36):8003-8010 4. [IF=11.413] Yan Yin et al."De novo biosynthesis of liquiritin in Saccharomyces cerevisiae."Acta Pharm Sin B. 2020 Apr;10:711 5. [IF=1.524] Zhang Xiaodong et al."Gene polymorphism of chalcone isomerase influence the accumulation of flavonoids in licorice (Glycyrrhiza spp.)."Genet Resour Crop Ev. 2021 Mar;68(3):899-913 6. [IF=6.793] Luo Xiaoning et al.Integrating full-length transcriptomics and metabolomics reveals the regulatory mechanisms underlying yellow pigmentation in tree peony (Paeonia suffruticosa Andr.) flowers.Hortic Res-England. 2021 Nov;8(1):1-15 7. [IF=4.57] Liu Jinyue et al."Identification and characterization of unique 5-hydroxyisoflavonoid biosynthetic key enzyme genes in Lupinus albus."Plant Cell Reports. 2021 Dec 01 |
Naringenin chalcone is an intermediate in flavonol biosynthesis and is spontaneously metabolized into naringenin (NAR) through chalcone isomerase. Naringenin chalcone has anti-inflammatory and anti-allergic effects.
biological activity | Naringenin chalcone is an intermediate in flavonol biosynthesis and is spontaneously metabolized into naringenin (NAR) through chalcone isomerase. Naringenin chalcone has anti-inflammatory and anti-allergic effects. |
chemical properties | soluble in methanol, ethanol, DMSO and other organic solvents. |
use | used for content determination/identification/pharmacological experiments, etc. |