(2E)-N-(2-Chloro-6-methylphenyl)-3-ethoxy-2-propenamide
(E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide
CAS: 863127-76-8
Molecular Formula: C12H14ClNO2
(2E)-N-(2-Chloro-6-methylphenyl)-3-ethoxy-2-propenamide - Names and Identifiers
| Name | (E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide |
| Synonyms | SKL777 (E)-N-(2-CHLORO-6-METHYLPHENYL)-3-ETHOXYACRYLAMIDE (Z)-N-(2-chloro-6-methylphenyl)-3-ethoxyacrylamide (E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide (E)-N-(2-chloro-6-methyl-phenyl)-3-ethoxyl acrylamide (2E)-N-(2-Chloro-6-methylphenyl)-3-ethoxy-2-propenamide 2-PropenaMide,N-(2-chloro-6-Methylphenyl)-3-ethoxy-, (2E)- (E)-N-(2-chloro-6-methylphenyl)-3-ethoxyacrylamide fandachem (E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide 863127-76-8 |
| CAS | 863127-76-8 |
| EINECS | 1312995-182-4 |
| InChI | InChI=1/C12H14ClNO2/c1-3-16-8-7-11(15)14-12-9(2)5-4-6-10(12)13/h4-8H,3H2,1-2H3,(H,14,15)/b8-7+ |
(2E)-N-(2-Chloro-6-methylphenyl)-3-ethoxy-2-propenamide - Physico-chemical Properties
| Molecular Formula | C12H14ClNO2 |
| Molar Mass | 239.7 |
| Density | 1.197 |
| Boling Point | 386.5±42.0 °C(Predicted) |
| pKa | 11.57±0.70(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.572 |
(2E)-N-(2-Chloro-6-methylphenyl)-3-ethoxy-2-propenamide - Introduction
(E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide, also known as (E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: colorless or light yellow liquid
-Molecular formula: C12H14ClNO2
-Molecular weight: 241.7g/mol
-Melting point: 66-68°C
-Boiling point: 345.6°C
-Solubility: Soluble in organic solvents such as ethanol, chloroform and dimethyl sulfoxide
Use:
(E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide has many applications in organic synthesis:
-It can be used as a crosslinking agent for the preparation of polymer materials, such as polymers and hydrogels.
-The compound can also be used to prepare additives such as flexible polymer coatings and thickeners.
-It can also be used as a component of fluorescent labeling reagents, biosensors and chemical sensors.
Preparation Method:
The preparation of (E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide is usually accomplished by the following steps:
1. First, 2-chloro-6-methylaniline reacts with ethoxyacryloyl chloride to generate (N-(2-chloro-6-methylphenyl) acrylamide-chloroethyl ester).
2. Then, the intermediate reacts with amine under basic conditions to produce the final product (E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide.
Safety Information:
Since (E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide is a chemical, it is necessary to pay attention to safety when using:
-Avoid direct contact with skin, eyes and mucous membranes. Wear chemical safety gloves, goggles and face shield when using.
-During use and storage, avoid exposure to open flames and high temperatures, and maintain a well-ventilated working environment.
-Consumption and inhalation of this compound is strictly prohibited. If ingestion or aspiration occurs, seek medical attention immediately.
Observe relevant safety regulations and operating procedures when handling and managing chemicals. If necessary, please consult and seek help from professionals.
Nature:
-Appearance: colorless or light yellow liquid
-Molecular formula: C12H14ClNO2
-Molecular weight: 241.7g/mol
-Melting point: 66-68°C
-Boiling point: 345.6°C
-Solubility: Soluble in organic solvents such as ethanol, chloroform and dimethyl sulfoxide
Use:
(E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide has many applications in organic synthesis:
-It can be used as a crosslinking agent for the preparation of polymer materials, such as polymers and hydrogels.
-The compound can also be used to prepare additives such as flexible polymer coatings and thickeners.
-It can also be used as a component of fluorescent labeling reagents, biosensors and chemical sensors.
Preparation Method:
The preparation of (E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide is usually accomplished by the following steps:
1. First, 2-chloro-6-methylaniline reacts with ethoxyacryloyl chloride to generate (N-(2-chloro-6-methylphenyl) acrylamide-chloroethyl ester).
2. Then, the intermediate reacts with amine under basic conditions to produce the final product (E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide.
Safety Information:
Since (E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide is a chemical, it is necessary to pay attention to safety when using:
-Avoid direct contact with skin, eyes and mucous membranes. Wear chemical safety gloves, goggles and face shield when using.
-During use and storage, avoid exposure to open flames and high temperatures, and maintain a well-ventilated working environment.
-Consumption and inhalation of this compound is strictly prohibited. If ingestion or aspiration occurs, seek medical attention immediately.
Observe relevant safety regulations and operating procedures when handling and managing chemicals. If necessary, please consult and seek help from professionals.
Last Update：2024-04-10 22:29:15
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