(2R)-2-(methoxymethyl)pyrrolidine - Names and Identifiers
(2R)-2-(methoxymethyl)pyrrolidine - Physico-chemical Properties
Molecular Formula | C6H13NO
|
Molar Mass | 115.17 |
Density | 0.932g/mLat 20°C(lit.) |
Boling Point | 61-62°C 40mm |
Specific Rotation(α) | -2.4o (C=2% IN BENZENE) |
Flash Point | 45°C |
Vapor Presure | 5.73mmHg at 25°C |
Appearance | Liquid |
Color | Clear colorless |
BRN | 4229755 |
pKa | 10.01±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Sensitive | Air Sensitive |
Refractive Index | n20/D 1.446 |
(2R)-2-(methoxymethyl)pyrrolidine - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | R10 - Flammable
R36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
UN IDs | UN 1993 3/PG 3 |
WGK Germany | 3 |
FLUKA BRAND F CODES | 3-10-34 |
HS Code | 29339900 |
Hazard Class | 3 |
Packing Group | III |
(2R)-2-(methoxymethyl)pyrrolidine - Introduction
The (R)-(-)-2-methymethyl pyrrolidine ((R)-(-)-2-methymethyl pyrrolidine) is an organic compound with the chemical formula C7H15NO and a molecular weight of 129.20g/mol.
Nature:
(R)-(-)-2-methymethyl pyrrolidine is a colorless to light yellow liquid with a special smell. It can be dissolved in many organic solvents, such as ethanol, ether and dichloromethane.
Use:
(R)-(-)-2-methymethyl pyrrolidine is widely used in organic synthesis. It can be used as catalyst, solvent and medium in various reactions. It is often used as a chiral inducer in drug synthesis to control the reaction to produce a specific stereochemical structure. In addition, it can also be used in natural product synthesis and chemical research in organic synthesis.
Preparation Method:
(R)-(-)-2-methymethyl pyrrolidine can be prepared by the reaction of pyrrolidine and methyl p-toluenesulfonate. The specific synthesis method can refer to the relevant organic synthesis literature or patent.
Safety Information:
The toxicity of the (R)-(-)-2-methymethyl pyrrolidine is relatively low, but the corresponding safety operation regulations still need to be observed. It may be irritating to the eyes and skin, so avoid direct contact during operation. It should be operated in a well-ventilated area and care should be taken to avoid inhaling its vapors. Wear appropriate personal protective equipment such as gloves, goggles and protective clothing during use. If inhaled or taken by mistake, seek medical attention immediately.
Last Update:2024-04-09 20:52:54