(2R,3R)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol - Names and Identifiers
Name | Hydroxybupropion (as (RS,RS)-cyclic Hemiketal)
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Synonyms | Hydroxybupropion (as (RS,RS)-cyclic Hydroxybupropion (as (RS,RS)-cyclic Hemiketal) (2R,3R)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol rel-(2R,3R)-2-(3-Chlorophenyl)-3,5,5-trimethylmorpholin-2-ol 2-Morpholinol, 2-(3-chlorophenyl)-3,5,5-trimethyl-, (2R,3R)-rel-
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CAS | 233600-52-7
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(2R,3R)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol - Physico-chemical Properties
Molecular Formula | C13H18ClNO2
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Molar Mass | 255.74 |
Storage Condition | 2-8℃ |
(2R,3R)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol - Introduction
Bupropion hydrochloride impurity (as (RS, RS)-cyclic hemik et al) is a drug impurity with the following chemical properties:
-Molecular formula: C13H18ClNO2
-Molecular weight: 259.74g/mol
-Appearance: colorless crystal or white to light yellow solid
-Solubility: Soluble in water and alcohol solvents, slightly soluble in non-polar solvents
-Melting point: About 148-150 ° C
Bupropion hydrochloride impurity is one of the main metabolites of the antidepressant drug bupropion, and its main purpose is to study the pharmacokinetics and in vivo transformation process of bupropion.
The synthesis method of bupropion hydrochloride impurities is more complicated. Generally, bupropion is metabolized in vivo or in vitro, and then purified and recrystallized to obtain pure products.
Safety information regarding the Bupropion Hydrochloride impurity requires careful handling and storage to avoid inhalation, ingestion, or contact with skin, eyes, and mucous membranes. Wear protective gloves, safety glasses and appropriate protective equipment to ensure good ventilation during use. If unexpected exposure or discomfort occurs, medical help should be sought immediately.
In addition, the impurity of bupropion hydrochloride is only used for experimental research purposes and is not suitable for human treatment. Follow relevant laboratory safety regulations and operating instructions during use.
Last Update:2024-04-09 21:54:55