(2R,3R,4R,5S)-6-(EthylaMino)hexane-1,2,3,4,5-pentaol
N-Ethyl Glucamine
CAS: 14216-22-9
Molecular Formula: C8H19NO5
(2R,3R,4R,5S)-6-(EthylaMino)hexane-1,2,3,4,5-pentaol - Names and Identifiers
| Name | N-Ethyl Glucamine |
| Synonyms | N-ethylgucamine n-ethylglucamine N-ETHYLGLUCAMINE N-Ethyl Glucamine N-ETHYL-D-GLUCAMINE N-Ethyl-D-glucamine 1-Ethylamino-1-deoxy-D-glucitol 1-(Ethylamino)-1-deoxy-D-glucitol (2R,3R,4R,5S)-6-(ethylamino)hexane-1,2,3,4,5-pentol (2R,3R,4R,5S)-6-(EthylaMino)hexane-1,2,3,4,5-pentaol |
| CAS | 14216-22-9 |
| EINECS | 238-073-8 |
| InChI | InChI=1/C8H19NO5/c1-2-9-3-5(11)7(13)8(14)6(12)4-10/h5-14H,2-4H2,1H3/t5-,6+,7+,8+/m0/s1 |
| InChIKey | IKXCHOUDIPZROZ-LXGUWJNJSA-N |
(2R,3R,4R,5S)-6-(EthylaMino)hexane-1,2,3,4,5-pentaol - Physico-chemical Properties
| Molecular Formula | C8H19NO5 |
| Molar Mass | 209.24 |
| Density | 1.320±0.06 g/cm3(Predicted) |
| Melting Point | 136-140 °C |
| Boling Point | 489.8±45.0 °C(Predicted) |
| Specific Rotation(α) | -17 º (c=1%, H2O) |
| Solubility | H2O: 0.1g/mL, clear, colorless |
| Appearance | White powder |
| Color | White to Off-White |
| pKa | 13.51±0.20(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Stability | Hygroscopic |
| MDL | MFCD03789564 |
| Physical and Chemical Properties | Melting point 136-140°C specific optical rotation -17 ° (c = 1%, H2O) |
(2R,3R,4R,5S)-6-(EthylaMino)hexane-1,2,3,4,5-pentaol - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 3-10-23 |
| HS Code | 29221990 |
(2R,3R,4R,5S)-6-(EthylaMino)hexane-1,2,3,4,5-pentaol - Introduction
Meglumine, also known as N,N-dimethyl-l-propylamine, is an organic compound. Here is some information about meglumine:
Nature:
Meglumine is a colorless liquid with a pungent odor. It is soluble in water, alcohol and ether solvents, but insoluble in petroleum ether.
Use:
Meglumine is mainly used as a fine chemical and pharmaceutical intermediate. It is widely used in polymer production, pharmaceutical industry and pesticide production. In medicine, meglumine can be used to synthesize a variety of drugs, such as antidepressants, local anesthetics and sedatives.
Preparation Method:
Meglumine is generally prepared by reacting methylamine with acetaldehyde (acetaldehyde acetal method) or by reacting methylamine with propionaldehyde (propionaldehyde acetal method). Lewis acid catalysts, such as aluminum nitride, are often used in the preparation process.
Safety Information:
When using meglumine, care should be taken to prevent direct contact with skin and eyes, and to operate in a well-ventilated place. Meglumine is irritating and may cause irritation to the skin and eyes. Therefore, appropriate protective equipment such as gloves and goggles should be worn during use. At the same time, it should be stored in a dark, dry and well-ventilated place, away from fire and oxidizing agents.
Nature:
Meglumine is a colorless liquid with a pungent odor. It is soluble in water, alcohol and ether solvents, but insoluble in petroleum ether.
Use:
Meglumine is mainly used as a fine chemical and pharmaceutical intermediate. It is widely used in polymer production, pharmaceutical industry and pesticide production. In medicine, meglumine can be used to synthesize a variety of drugs, such as antidepressants, local anesthetics and sedatives.
Preparation Method:
Meglumine is generally prepared by reacting methylamine with acetaldehyde (acetaldehyde acetal method) or by reacting methylamine with propionaldehyde (propionaldehyde acetal method). Lewis acid catalysts, such as aluminum nitride, are often used in the preparation process.
Safety Information:
When using meglumine, care should be taken to prevent direct contact with skin and eyes, and to operate in a well-ventilated place. Meglumine is irritating and may cause irritation to the skin and eyes. Therefore, appropriate protective equipment such as gloves and goggles should be worn during use. At the same time, it should be stored in a dark, dry and well-ventilated place, away from fire and oxidizing agents.
Last Update：2024-04-09 21:11:58
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