(2R,4R)

(2R,4R) - Names and Identifiers

Name	1,2-Pyrrolidinedicarboxylicacid, 4-amino-, 1-(1,1-dimethylethyl) ester, (2R,4R)-
Synonyms	(2R,4R) N-boc-cis-4-AMino-D-Proline 1-N-BOC-4(R)-AMINO-PYRROLIDINE-2(R)-CARBOXYLIC ACID (2R,4R)-4-amino-1-Boc-pyrrolidine-2-carboxylic acid (2R,4R)-1-BOC-4-AMINO-PYRROLIDINE-2-CARBOXYLIC ACID (2R,4R)-4-Amino-1,2-pyrrolidinedicarboxylic acid 1-(tert-butyl) ester (2R,4R)-4-Amino-1,2-Pyrrolidinedicarboxylicacid 1-(1,1-dimethylethyl) ester (2R-cis)-4-Amino-1,2-Pyrrolidinedicarboxylicacid 1-(1,1-dimethylethyl) ester 1,2-Pyrrolidinedicarboxylicacid, 4-amino-, 1-(1,1-dimethylethyl) ester, (2R,4R)- 1,2-Pyrrolidinedicarboxylicacid, 4-amino-, 1-(1,1-dimethylethyl) ester, (2R-cis)-
CAS	132622-98-1

(2R,4R) - Physico-chemical Properties

Molecular Formula	C10H18N2O4
Molar Mass	230.26
Density	1.232
Melting Point	263-264℃
Boling Point	371.1±42.0 °C(Predicted)
pKa	3.65±0.20(Predicted)
Storage Condition	2-8°C

(2R,4R) - Risk and Safety

Hazard Class

IRRITANT

(2R,4R) - Introduction

1-N-BOC-4(R)-amino-pyrrolidine-2 (R)-carboxylic acid is an organic compound also known as N-Boc-4(R)-amino-pyrrolidine-2 (R)-carboxylic acid. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance is white or off-white solid.
-May have a special odor.
-The melting point is about 50-55°C.
-The molecular formula is C12H17NO4, and the relative molecular mass is 235.27g/mol.

Use:
- 1-N-BOC-4(R)-Amino-pyrrolidine-2 (R)-carboxylic acid is a common organic synthesis intermediate.
-In the field of drug synthesis, it can be used to synthesize various chiral compounds.
-It can also be used as a protecting group in organic synthesis to protect the hydroamine functional group.

Preparation Method:
The preparation of -1-N-BOC-4(R)-amino-pyrrolidine-2 (R)-carboxylic acid generally involves N-Boc protection of 4-amino-pyrrolidine-2 (R)-carboxylic acid.
-The specific step can be obtained by reacting 4-amino-pyrrolidine-2 (R)-carboxylic acid with N-tert-butoxycarbonylisopropylamine or N-tert-butoxycarbonyldimethylamine in a suitable solvent.

Safety Information:
The safety information for -1-N-BOC-4(R)-amino-pyrrolidine-2 (R)-carboxylic acid requires good laboratory practice and appropriate personal protective measures.
-Avoid direct contact with skin, eyes and clothing during use.
-When necessary, operate in a well-ventilated place to avoid inhaling dust or gas.
-It is necessary to strictly comply with relevant safety operation procedures and handling specifications to ensure safe operation.

Last Update：2024-04-09 02:00:42