(2S)-1,1-Diphenyl-1,2-propanediol

(2S)-1,1-Diphenyl-1,2-propanediol - Names and Identifiers

Name	S(-)-1,1-diphenyl-1,2-propanediol
Synonyms	(S)-1,1-Diphenylpropane-1,2-diol S(-)-1,1-diphenyl-1,2-propanediol (2S)-1,1-Diphenyl-1,2-propanediol (2S)-1,1-diphenylpropane-1,2-diol (S)-(?-1,1-Diphenyl-1,2-propanediol (S)-(-)-1,1-DIPHENYL-1,2-PROPANEDIOL 1,2-Propanediol, 1,1-diphenyl-, (2S)-
CAS	46755-94-6
EINECS	258-258-3
InChI	InChI=1/C15H16O2/c1-12(16)15(17,13-8-4-2-5-9-13)14-10-6-3-7-11-14/h2-12,16-17H,1H3/t12-/m0/s1

(2S)-1,1-Diphenyl-1,2-propanediol - Physico-chemical Properties

Molecular Formula	C15H16O2
Molar Mass	228.29
Density	1.152±0.06 g/cm3(Predicted)
Melting Point	89-92°C(lit.)
Boling Point	406.6±40.0 °C(Predicted)
Flash Point	195.7°C
Vapor Presure	2.43E-07mmHg at 25°C
BRN	3202232
pKa	13.28±0.29(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.596

(2S)-1,1-Diphenyl-1,2-propanediol - Risk and Safety

Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3

(2S)-1,1-Diphenyl-1,2-propanediol - Introduction

S(-)-1,1-diphenyl-1,2-propanediol is a chiral compound consisting of the S(-) isomer of the chiral isomers of 1,1-diphenyl-1,2-propanediol. It is a colorless solid with a faint sweet taste at room temperature.

S(-)-1,1-diphenyl-1,2-propanediol is mainly used as a chiral resolution reagent and a raw material for chiral synthesis. It can be used as a catalyst for asymmetric synthesis reactions, such as hydrogenation and oxidation reactions. In addition, it also has important applications in drug synthesis and can be used as intermediates for the synthesis of chiral drugs.

The method for preparing S(-)-1,1-diphenyl-1,2-propanediol is mainly carried out by chiral resolution. A common method of preparation is by symmetric or asymmetric catalytic hydrogenation.

Regarding safety information, S(-)-1,1-diphenyl-1,2-propanediol needs to follow the usual chemical laboratory safety procedures when used in the laboratory. It is less toxic, but it still needs to be protected from contact with skin, eyes and inhalation. Wear appropriate chemical protective gloves and eye protection during use. If you are accidentally exposed or taken by mistake, please call your doctor immediately.

Last Update：2024-04-09 20:02:46