(2S)-4-氧代-1,2-吡咯烷二甲酸二叔丁酯

(2S)-4-氧代-1,2-吡咯烷二甲酸二叔丁酯 - Names and Identifiers

Name	BOC-4-OXO-L-PROLINE TERT-BUTYL ESTER
Synonyms	K204 Boc-4-OXO-Pro-OtBu BOC-4-OXO-L-PROLINE TERT-BUTYL ESTER N-BOC-4-OXO-L-PROLINE TERT-BUTYL ESTER 1-(tert-butoxycarbonyl)-4-oxo-L-proline N-T-BOC-4-OXO-L-PROLINE TERT-BUTYL ESTER ditert-butyl (2S)-4-oxopyrrolidine-1,2-dicarboxylate di-tert-butyl (2S)-4-oxopyrrolidine-1,2-dicarboxylate (2S) tert-butyl N-(tert-butoxycabonyl)-4-oxoprolinate 1,2-di-tert-butyl (2S)-4-oxopyrrolidine-1,2- dicarboxylate
CAS	166410-05-5
InChI	InChI=1/C10H15NO5/c1-10(2,3)16-9(15)11-5-6(12)4-7(11)8(13)14/h7H,4-5H2,1-3H3,(H,13,14)/t7-/m0/s1

(2S)-4-氧代-1,2-吡咯烷二甲酸二叔丁酯 - Physico-chemical Properties

Molecular Formula	C14H23NO5
Molar Mass	285.34
Density	1.138±0.06 g/cm3(Predicted)
Melting Point	64-67°C
Boling Point	366.7±42.0 °C(Predicted)
Flash Point	190.123°C
Vapor Presure	0mmHg at 25°C
pKa	-3.86±0.40(Predicted)
Storage Condition	Sealed in dry,Store in freezer, under -20°C
Refractive Index	1.516

(2S)-4-氧代-1,2-吡咯烷二甲酸二叔丁酯 - Introduction

BOC-4-OXO-L-PROLINE TERT-BUTYL ESTER is an organic compound with the chemical formula C13H21NO6. It is a white solid, stable at room temperature. The following describes its nature, use, preparation and safety information:

Nature:
BOC-4-OXO-L-PROLINE TERT-BUTYL ESTER has low solubility and is soluble in organic solvents such as dimethylformamide (DMF) and dichloromethane. It is a stable compound that does not easily decompose at room temperature. Its molecular structure contains oxygen (-COOR) and Boc protecting groups, which make it have certain chemical activity in organic synthesis.

Use:
BOC-4-OXO-L-PROLINE TERT-BUTYL ESTER is often used as an intermediate in organic synthesis. Because its structure contains amino acid groups, it is often used in the synthesis of peptide compounds. By controlling the reaction conditions, the Boc protecting group can be removed to obtain a free amino acid, which can be used to synthesize natural proteins, drugs and other biologically active molecules.

Method:
There are many methods for preparing BOC-4-OXO-L-PROLINE TERT-BUTYL ESTER. One common method is to acidify proline with tert-butyl alcohol to generate proline tert-butyl ESTER, and then esterify it with acetic anhydride to generate BOC-4-OXO-L-PROLINE TERT-BUTYL ESTER.

Safety Information:
BOC-4-OXO-L-PROLINE TERT-BUTYL ESTER is a relatively safe compound under normal use conditions. However, it is subject to some regular laboratory safety measures. Wear suitable personal protective equipment such as laboratory gloves and goggles when handling the compound. At the same time, it should be operated under well-ventilated laboratory conditions to avoid its potential impact on the human body and the environment.

Last Update：2024-04-09 21:11:58