(2r,3r)-(-)-1,4-Bis(Diphenyl

(2r,3r)-(-)-1,4-Bis(Diphenyl - Names and Identifiers

Name	(-)-2,2-dimethyl-4,5-((diphenylphosphino)dimethyl)dioxolane
Synonyms	(-)-diop (2r,3r)-(-)-1,4-Bis(Diphenyl )-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(dipheny (-)-2,2-dimethyl-4,5-((diphenylphosphino)dimethyl)dioxolane (4R,5R)-(-)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane (-)-DIOP (-)-2,2-dimethyl-4,5-((diphenylphosphino)dimethyl)dioxolane (4R,5R)-(-)-2,2-Dimethyl-4,5-bis((diphenylphosphino)methyl)-1,3-dioxolane [(2,2-dimethyl-1,3-dioxolane-4,5-diyl)dimethanediyl]bis(diphenylphosphane) {[(4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-diyl]dimethanediyl}bis(diphenylphosphane) (4R,5R)-(-)-4,5-Bis(diphenylphosphinoMethyl)-2,2-diMethyl-1,3-dioxolane,(R,R)-DIOP. (4R,5R)-(-)-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane(-)-DIOP(2R,3R)-(-)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane
CAS	32305-98-9
EINECS	250-984-2
InChI	InChI=1/C31H32O2P2/c1-31(2)32-29(23-34(25-15-7-3-8-16-25)26-17-9-4-10-18-26)30(33-31)24-35(27-19-11-5-12-20-27)28-21-13-6-14-22-28/h3-22,29-30H,23-24H2,1-2H3/t29-,30-/m0/s1

(2r,3r)-(-)-1,4-Bis(Diphenyl - Physico-chemical Properties

Molecular Formula	C31H32O2P2
Molar Mass	498.54
Melting Point	88-90°C(lit.)
Boling Point	590.3±25.0 °C(Predicted)
Specific Rotation(α)	-26° (c 2.0, CHCl3)
Flash Point	390.9°C
Vapor Presure	2.75E-13mmHg at 25°C
Appearance	Powder
Color	white
BRN	1441045
Storage Condition	2-8°C
Sensitive	Air Sensitive
MDL	MFCD00014107

(2r,3r)-(-)-1,4-Bis(Diphenyl - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves.
WGK Germany	3
FLUKA BRAND F CODES	10-23
TSCA	No
HS Code	29329990

(2r,3r)-(-)-1,4-Bis(Diphenyl - Introduction

(-)-2,2-dimethyl-4,5-((diphenylphosphino)dimethyl)dioxolane is an organic compound with the chemical formula C21H23O2P, the chemical structure contains two diphenylphosphine groups and a dioxa six-membered ring.

(-)-2,2-dimethyl-4,5-((diphenylphosphino)dimethyl)dioxolane is often used as a chiral ligand and is widely used in Chiral synthesis reactions in organic synthesis, and can be used to catalyze asymmetric carbonyl reaction, asymmetric coupling reaction and asymmetric hydrogenation reaction. Its chiral structure makes it possible to promote selectivity in the reaction process.

The preparation of (-)-2,2-dimethyl-4,5-((diphenylphosphino)dimethyl)dioxolane typically involves the reaction of dihydroxy-1, 4-bis-diphenylphosphinobutane with isoacrylonitrile. Detailed procedures and conditions for the specific preparation can be found in the scientific literature.

Regarding safety information, according to the available information, there are relatively few studies on the toxicity and danger of (-)-2,2-dimethyl-4,5-((diphenylphosphino)dimethyl)dioxolane. However, as an organic compound, it may have some potential hazards, such as irritation and corrosiveness. Therefore, the appropriate laboratory practices should be observed during use and the necessary safety measures should be taken, including the wearing of appropriate personal protective equipment.

Last Update：2024-04-10 22:29:15