(3,3-Difluorocyclobutyl)m...

(3,3-Difluorocyclobutyl)m... - Names and Identifiers

Name	(3,3-difluorocyclobutyl)methanol
Synonyms	LogP (3,3-Difluorocyclobutyl)m... (3,3-Difluorocyclobutyl)methanol (3,3-difluorocyclobutyl)methanol 3,3-Difluoro-cyclobutanemethanol (3,3-DIFLUOROCYCLOBUTYL)METHANOL Cyclobutanemethanol, 3,3-difluoro- CyclobutaneMethanol, 3,3-difluoro-
CAS	681128-39-2
InChI	InChI=1/C5H8F2O/c6-5(7)1-4(2-5)3-8/h4,8H,1-3H2
InChIKey	MDZKTVVUZBIKGI-UHFFFAOYSA-N

(3,3-Difluorocyclobutyl)m... - Physico-chemical Properties

Molecular Formula	C5H8F2O
Molar Mass	122.11
Density	1.2g/ml
Boling Point	130.9±10.0 °C(Predicted)
Flash Point	32.994°C
Vapor Presure	4.221mmHg at 25°C
Appearance	clear liquid
Color	Colorless to Almost colorless
pKa	15.05±0.10(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.40

(3,3-Difluorocyclobutyl)m... - Introduction

(3,3-difluorocycloutyl) methanol is an organic compound with the chemical formula C5H9F2OH. The following describes its nature, use, preparation and safety information:

Nature:
(3,3-difluorocyclomutyl) methanol is a colorless liquid with a lower boiling point and melting point. It is a flammable liquid that can produce a flammable mixture with a fire source in the air. It is stable at room temperature, but can react with some strong oxidants. It is soluble in many organic solvents, such as ethanol and ether.

Use:
(3,3-difluorocycloutyl) methanol is an important intermediate in organic synthesis. It can be used to prepare a variety of organic compounds, such as pesticides, drugs, polymer materials, etc. It also has applications in the pharmaceutical field for the synthesis of pharmaceutical raw materials. In addition, it can be used as a solvent or reactant in chemical research.

Preparation Method:
(3,3-difluorocyclomutyl) methanol can be obtained by a two-step synthesis. First, 2,2,3,3-tetrafluoroacetone is reacted with trifluoromethylsulfamide to yield 2,2, 3,3-tetrafluoro-1-thioacetone. Then, starting from 1-bromo-2, 2,3, 3-tetrafluoropropene, it is reacted with ethanol in the presence of a base to carry out an alcoholation reaction to produce the target product (3,3-difluorocycloutyl) methanol.

Safety Information:
(3,3-difluorocyclomutyl) methanol is an organic compound with a certain degree of danger. It is irritating to the eyes and skin and may cause eye and skin damage. When using should pay attention to protective measures, avoid direct contact with skin and eyes, wear appropriate protective glasses and gloves. It is a flammable liquid and needs to be kept away from fire and high temperatures. During storage and use, attention should be paid to a well-ventilated environment and to avoid inhalation of its vapors. In the event of an accident, appropriate first aid and treatment measures shall be taken immediately.

Last Update：2024-04-09 21:01:54