(3R)-3-Amino-3-(4-fluorophenyl)propan-1-ol

(3R)-3-Amino-3-(4-fluorophenyl)propan-1-ol - Names and Identifiers

Name	(3R)-3-Amino-3-(4-fluorophenyl)propan-1-ol
Synonyms	(R)-3-(4-Fluorophenyl)-β-alaninol (R)-3-(4-FLUOROPHENYL)-BETA-ALANINOL (R)-3-Amino-2-(4-fluorophenyl)propan-1-ol (3R)-3-Amino-3-(4-fluorophenyl)propan-1-ol Benzenepropanol, gamma-amino-4-fluoro-, (gammaR)- Benzenepropanol, .gamma.-amino-4-fluoro-, (.gamma.R)-
CAS	228422-47-7
InChI	InChI=1/C9H12FNO/c10-8-3-1-7(2-4-8)9(11)5-6-12/h1-4,9,12H,5-6,11H2/t9-/m1/s1

(3R)-3-Amino-3-(4-fluorophenyl)propan-1-ol - Physico-chemical Properties

Molecular Formula	C9H12FNO
Molar Mass	169.1960832
Density	1.168g/cm³
Boling Point	296.827°C at 760 mmHg
Flash Point	133.316°C
Vapor Presure	0.001mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.541

(3R)-3-Amino-3-(4-fluorophenyl)propan-1-ol - Introduction

(3R)-3-Amino-3-(4-fluorophenyl)propan-1-ol, also known as (3R)-3-Amino-3-(4-fluorophenyl)propan-1-ol, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
(3R)-3-Amino-3-(4-fluorophenyl)propan-1-ol is a white or off-white crystalline solid. Its molecular formula is C9H12FNO and its molecular weight is 167.2. The compound is soluble in water and most organic solvents at room temperature. It has chirality, in which the (3R)-3-Amino-3-(4-fluorophenyl)propan-1-ol is optically active.

Use:
(3R)-3-Amino-3-(4-fluorophenyl)propan-1-ol is commonly used as a chiral catalyst in organic synthesis. It also has some applications in the field of medicine. For example, it can be used as an intermediate in the synthesis of certain chiral drugs, such as antiepileptic drugs and antipsychotic drugs. In addition, it can also be used in the synthesis of certain pesticides and chemicals.

Method:
(3R)-3-amino-3-(4-fluorophenyl)propan-1-ol can be prepared by a variety of routes. One commonly used method is by first synthesizing (3R)-3-aminopropanol, which is then p-fluorophenylated under reaction conditions. As the catalyst, a metal catalyst such as a palladium catalyst or a nickel catalyst is commonly used.

Safety Information:
(3R)-3-Amino-3-(4-fluorophenyl)propan-1-ol has low toxicity, but it is still necessary to pay attention to safe operation. It is a combustible and should be kept away from open flames and high temperatures. Wear protective gloves and glasses to ensure adequate ventilation during operation. If the skin or eyes are exposed, rinse immediately with water and seek medical assistance.

Last Update：2024-04-09 20:52:54