(3R)-3-Dimethylaminopyrrolidine
(3R)-(+)-3-(Dimethylamino)Pyrrolidine
CAS: 132958-72-6
Molecular Formula: C6H14N2
(3R)-3-Dimethylaminopyrrolidine - Names and Identifiers
(3R)-3-Dimethylaminopyrrolidine - Physico-chemical Properties
| Molecular Formula | C6H14N2 |
| Molar Mass | 114.19 |
| Density | 0.899g/mLat 25°C(lit.) |
| Boling Point | 166°C760mm Hg(lit.) |
| Flash Point | 125°F |
| Vapor Presure | 2.73mmHg at 25°C |
| Appearance | clear liquid |
| Color | Colorless to Light yellow |
| pKa | 9.93±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Sensitive | Air Sensitive |
| Refractive Index | n20/D 1.4650(lit.) |
| Physical and Chemical Properties | WGK Germany:2 |
(3R)-3-Dimethylaminopyrrolidine - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R10 - Flammable R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes R38 - Irritating to the skin R37 - Irritating to the respiratory system |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/39 - S39 - Wear eye / face protection. S36 - Wear suitable protective clothing. |
| UN IDs | UN 1993 3/PG 3 |
| WGK Germany | 2 |
| HS Code | 29339900 |
| Hazard Class | 3 |
| Packing Group | III |
(3R)-3-Dimethylaminopyrrolidine - Introduction
(3R)-( )-3-dimethylaminopyrrolidine is a chiral compound with a chemical formula of C8H14N2 and a relative molecular mass of 138.21g/mol. It is a solid, soluble in solvents such as ethanol and chloroform.
This compound has a wide range of applications in pharmaceuticals and organic synthesis. It is an effective chiral reagent for chiral catalytic reactions and asymmetric synthesis. It can also be used in the synthesis of chiral drug molecules and ligands, and plays an important role in the pharmaceutical industry.
(3R)-( )-3-dimethylaminopyrrolidine has a variety of preparation methods, one of which is a common method by phthalic acid diester under the action of a reducing agent (such as diethyltin) Reaction with benzylamine to obtain the target product.
Regarding safety information,(3R)-( )-3-dimethylaminopyrrolidine is relatively safe under correct use and storage. However, it is still a chemical, and care should be taken to avoid direct contact with the skin and eyes, and to ensure that it is operated in a well-ventilated place.
Most chemicals should be stored and handled properly to prevent accidental spills or hazards. When using, please follow the relevant safety procedures and refer to the safety data form (SDS) of the compound for more specific safety information.
This compound has a wide range of applications in pharmaceuticals and organic synthesis. It is an effective chiral reagent for chiral catalytic reactions and asymmetric synthesis. It can also be used in the synthesis of chiral drug molecules and ligands, and plays an important role in the pharmaceutical industry.
(3R)-( )-3-dimethylaminopyrrolidine has a variety of preparation methods, one of which is a common method by phthalic acid diester under the action of a reducing agent (such as diethyltin) Reaction with benzylamine to obtain the target product.
Regarding safety information,(3R)-( )-3-dimethylaminopyrrolidine is relatively safe under correct use and storage. However, it is still a chemical, and care should be taken to avoid direct contact with the skin and eyes, and to ensure that it is operated in a well-ventilated place.
Most chemicals should be stored and handled properly to prevent accidental spills or hazards. When using, please follow the relevant safety procedures and refer to the safety data form (SDS) of the compound for more specific safety information.
Last Update：2024-04-09 20:45:29
