(3R)-3-aMino-4-(2,4,5-trifluorophenyl)butanoate

(3R)-3-aMino-4-(2,4,5-trifluorophenyl)butanoate - Names and Identifiers

Name	Benzenebutanoic acid, b-amino-2,4,5-trifluoro-, methyl ester, (bR)-
Synonyms	Sitagliptin Impurity 51 (R)-Sitagliptin Methyl-Ester IMpurity (R)-methyl 3-amino-4-(2,4,5-trifluorophenyl) (3R)-3-aMino-4-(2,4,5-trifluorophenyl)butanoate Methyl (R)-b-Amino-2,4,5-F3-benzenebutanoate HCl (R)-Methyl 3-aMino-4-(2,4,5-trifluoro phenyl) butanoate Benzenebutanoicacid,b-aMino-2,4,5-trifluoro-,Methylester,(bR)- Benzenebutanoic acid,3-amino-2,4,5-trifluoro-, methyl ester, (3R)- Benzenebutanoic acid, b-amino-2,4,5-trifluoro-, methyl ester, (bR)- Benzenebutanoic acid, β-amino-2,4,5-trifluoro-, methyl ester, (βR)-
CAS	881995-69-3
EINECS	1312995-182-4

(3R)-3-aMino-4-(2,4,5-trifluorophenyl)butanoate - Physico-chemical Properties

Molecular Formula	C11H12F3NO2
Molar Mass	247.21
Density	1.287±0.06 g/cm3(Predicted)
Boling Point	316.0±42.0 °C(Predicted)
pKa	6.90±0.10(Predicted)
Storage Condition	2-8°C

(3R)-3-aMino-4-(2,4,5-trifluorophenyl)butanoate - Introduction

Benzenebutanoic acid, b-amino-2, 4,5-trifluororo-, methyl ester, (bR)-, also known as (bR)-trifluorophenylacetic acid methyl ester, is an organic compound. The following is an introduction to its nature, use, preparation and safety information:

Nature:
-Appearance: Usually solid, can be white to yellow crystalline or powdery substance.
-Melting point: about 80-84°C.
-Solubility: Soluble in organic solvents, such as ether and dichloromethane.

Use:
- Benzenebutanoic acid, b-amino-2,4,5-trifluoro-, methyl ester, (bR)-can be used as pharmaceutical intermediates and reagents, and can be used in asymmetric synthesis in organic synthesis and other fields.

Preparation Method:
- Benzenebutanoic acid, b-amino-2,4,5-trifluoro-, methyl ester, (bR)-the preparation method is more complicated, usually obtained from other compounds through multiple reactions. Specific synthesis path can be designed according to specific needs.

Safety Information:
- Benzenebutanoic acid, b-amino-2, 4,5-trifluororo-, methyl ester, (bR)-has no obvious danger or toxicity under normal use conditions. However, as a chemical, it can have adverse effects on specific populations or the environment. When using or handling, it is recommended to follow safe operating procedures and avoid contact with skin, eyes and respiratory system.

Last Update：2024-04-09 20:45:29