(3S)-(-)-3-(Trifluoroacetamido)pyrrolidine

(3S)-(-)-3-(Trifluoroacetamido)pyrrolidine - Names and Identifiers

Name	(3S)-(-)-3-(TRIFLUOROACETAMIDO)PYRROLIDINE HYDROCHLORIDE
Synonyms	(S)-3-(Trifluoroacetamido)pyrrolidine HCl (3S)-(-)-3-(Trifluoroacetamido)pyrrolidine (3S)-(-)-3-(Trifluoroacetamido)pyrrolidineHCl 2,2,2-trifluoro-N-[(3S)-pyrrolidin-3-yl]acetamide 2,2,2-trifluoro-N-((S)-pyrrolidin-3-yl)acetamide HCl (3S)-(-)-3-(TRIFLUOROACETAMIDO)PYRROLIDINE HYDROCHLORIDE (S)-2,2,2-Trifluoro-N-(pyrrolidin-3-yl)acetaMide hydrochloride
CAS	132883-43-3
InChI	InChI=1/C6H9F3N2O/c7-6(8,9)5(12)11-4-1-2-10-3-4/h4,10H,1-3H2,(H,11,12)/t4-/m0/s1

(3S)-(-)-3-(Trifluoroacetamido)pyrrolidine - Physico-chemical Properties

Molecular Formula	C6H10ClF3N2O
Molar Mass	218.6
Density	1.31g/cm³
Melting Point	233 °C
Boling Point	241.5°C at 760 mmHg
Flash Point	99.9°C
Water Solubility	almost transparency
Vapor Presure	0.0357mmHg at 25°C
Appearance	powder to crystal
Color	White to Almost white
Storage Condition	2-8℃
Refractive Index	-27 ° (C=1, H2O)

(3S)-(-)-3-(Trifluoroacetamido)pyrrolidine - Introduction

(3S)-(-)-3-(trifluoroacetamido) pyrrolidine hydrochloride, also known as (R)-(-)-3-(trifluoroacetamido) pyrrolidine hydrochloride, is an organic compound. Specific properties are as follows:

Nature:
-Appearance: White crystalline solid
-Melting point: about 150-152°C
-Solubility: Soluble in water, ethanol and acetone

Use:
The compound is commonly used as a chiral resolution reagent and a chiral recognition reagent. It can be used in the synthesis of chiral reagents and intermediates, for chiral control of synthetic drugs and pesticides, and for chiral selective catalytic reactions. In addition, it can also be used to prepare chiral glyphosate and other chiral compounds.

Preparation Method:
The preparation of (3S)-(-)-3-(trifluoroacetamido) pyrrolidine hydrochloride is generally achieved by a catalyst-mediated reaction with chiral selectivity. The specific preparation method can be searched according to the literature.

Safety Information:
-The compound should be used in a laboratory environment in strict accordance with safe operating procedures.
-Avoid contact with skin, eyes and respiratory system. In case of contact, rinse with water and seek medical help.
-Should be stored in a dry, cool place, away from fire and oxidizing agents.
-During handling and storage, keep the identification of the compound clearly visible to avoid misuse or confusion.
-For detailed safety information on this compound, the operator should consult the relevant safety data and MSDS (safety data sheet).

Last Update：2024-04-09 20:52:54