(3S)-1-methyl-3-phenylpiperazinediium

(3S)-1-methyl-3-phenylpiperazinediium - Names and Identifiers

Name	1-Methyl-3-phenyl-piperazine
Synonyms	1-Methyl-3-phenyl 1-METHYL-3-PHENYLPIPERAZINE 1-Methyl-3-phenylpiperazine 1-Methyl-3-phenyl-piperazine 1-N-METHYL-3-PHENYL-PIPERAZINE DL-1-Methyl-3-phenyl-piperazine (3R)-1-methyl-3-phenylpiperazinediium (3S)-1-methyl-3-phenylpiperazinediium Piperazine, 1-methyl-3-phenyl- (7CI,8CI,9CI) (3S)-1-methyl-3-phenyl-2,3,5,6-tetrahydropyrazine
CAS	5271-27-2
EINECS	432-360-3
InChI	InChI=1/C11H16N2/c1-13-8-7-12-11(9-13)10-5-3-2-4-6-10/h2-6,11-12H,7-9H2,1H3/p+2/t11-/m1/s1
InChIKey	IRMBVBDXXYXPEW-UHFFFAOYSA-N

(3S)-1-methyl-3-phenylpiperazinediium - Physico-chemical Properties

Molecular Formula	C11H16N2
Molar Mass	176.26
Density	0.991±0.06 g/cm3(Predicted)
Melting Point	56-60 °C (lit.)
Boling Point	85 °C
Flash Point	85°C/0.5mm
Water Solubility	soluble
Solubility	DMSO (Slightly), Methanol (Slightly)
Vapor Presure	0.00382mmHg at 25°C
Appearance	Needles or Crystals
Color	Pale yellow
pKa	8.52±0.40(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Sensitive	Air Sensitive
MDL	MFCD03411603

(3S)-1-methyl-3-phenylpiperazinediium - Risk and Safety

Risk Codes	R25 - Toxic if swallowed R34 - Causes burns R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN 2923 8/PG 3
WGK Germany	3
HS Code	29335990
Hazard Note	Irritant
Hazard Class	8
Packing Group	III

(3S)-1-methyl-3-phenylpiperazinediium - Introduction

1-Methyl-3-phenyl-piperazine is an organic compound containing methyl and phenyl substituted piperazine rings in its structure. The following is a description of its nature, use, preparation and safety information:

Nature:
1-Methyl-3-phenyl-piperazine is a white crystalline solid with the formula C12H16N2. It has moderate solubility and is soluble in some polar organic solvents such as ethanol and dimethyl sulfoxide. The compound can undergo photo-oxidation reaction under certain conditions.

Use:
1-Methyl-3-phenyl-piperazine is widely used as an intermediate in organic synthesis in chemical research. Such compounds can be used as building blocks for drug molecules, for example, in the development of antidepressant drugs, l-Methyl-3-phenyl-piperazine can be used as a starting material. In addition, it can also be used to prepare other organic compounds, such as dyes and functional materials.

Preparation Method:
1-Methyl-3-phenyl-piperazine can be prepared by a variety of methods. One commonly used method is by iodination of phenyl -1-methyl piperazine and iodide. The specific steps include reacting phenyl -1-methyl piperazine with sodium iodide or lead iodide to produce 1-Methyl-3-phenyl-piperazine and obtain the corresponding iodide, and finally removing iodine by reduction.

Safety Information:
1-Methyl-3-phenyl-piperazine is generally less toxic when used and stored correctly. However, as a chemical substance, it may cause certain irritation and sensitivity to the human body. Therefore, appropriate safety measures should be taken during operation, including wearing protective gloves and glasses to avoid direct contact. In addition, the compound should be stored properly to prevent fire and other dangerous situations. When dealing with problems or security concerns, it is best to consult a professional.

Last Update：2024-04-09 21:32:41