(3S)-3-Aminohexahydro-1-methyl-2H-azepin-2-one

(3S)-3-Aminohexahydro-1-methyl-2H-azepin-2-one - Names and Identifiers

Name	(3S)-3-amino-1-methyl-azepan-2-one
Synonyms	(S)-3-amino-1-methylazepan-2-one 3S)-3-Amino-1-methylazepan-2-one (3S)-3-amino-1-methyl-2-azepanone (3S)-3-Amino-1-methylazepan-2-one (3S)-3-amino-1-methyl-azepan-2-one (S)-3-AMino-1-Methyl-azepan-2-one HCl (3S)-3-Aminohexahydro-1-methyl-2H-azepin-2-one 2H-Azepin-2-one, 3-aminohexahydro-1-methyl-, (3S)-
CAS	209983-96-0
InChI	InChI=1/C7H14N2O/c1-9-5-3-2-4-6(8)7(9)10/h6H,2-5,8H2,1H3/t6-/m0/s1

(3S)-3-Aminohexahydro-1-methyl-2H-azepin-2-one - Physico-chemical Properties

Molecular Formula	C7H14N2O
Molar Mass	142.2
Density	1.020
Boling Point	274℃
Flash Point	119℃
Vapor Presure	0.00566mmHg at 25°C
pKa	8.81±0.20(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.48

(3S)-3-Aminohexahydro-1-methyl-2H-azepin-2-one - Introduction

(3S)-3-amino-1-methyl-azepan-2-one, also known as (D)-α-amino-γ-aminobutanone, is a chiral compound. Its chemical formula is C8H15NO and its molecular weight is 141.21g/mol. The following is an introduction to some of its properties, uses, methods and safety information:

Nature:
-Appearance: Colorless crystalline or white solid.
-Melting point: About 159-160 ℃.
-Boiling point: About 201-202 ℃.
-Solubility: Soluble in polar solvents such as water, ethanol and ether.

Use:
- (3S)-3-amino-1-methyl-azepan-2-one is widely used in the field of Chiral synthesis in organic synthesis, and can be used as chiral catalyst, chiral ligand or chiral raw material intermediate. It has important applications in drug synthesis, hormone synthesis, natural product synthesis and other fields.

Method:
The preparation method of (3S)-3-amino-1-methyl-azepan-2-one is mainly obtained by synthetic reaction. A common method of preparation is by carrying out the formation of the corresponding hydrogen and C- C bonds. Specific methods may include asymmetric hydrogenation, asymmetric addition of amides, and asymmetric catalysis.

Safety Information:
- (3S)-3-amino-1-methyl-azepan-2-one is currently not listed as a particularly dangerous substance, but it still needs to be used and handled correctly.
-Wear appropriate protective equipment such as laboratory gloves, goggles and laboratory top when handling the compound.
-Avoid inhalation, ingestion or contact with skin and eyes.
-Standard safe operating procedures should be followed during storage and handling.

Last Update：2024-04-09 02:00:44