(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZENE - Names and Identifiers
Name | (4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzene
|
Synonyms | Phenylpinacolborane (Pinacolboryl)benzene Pinacol phenylboronate Phenylboronic acid pinacol ester PHENYL-BORONIC ACID PINACOL ESTER Phenyl-boronic acid pinacol ester Benzeneboronic acid, pinacol ester 4,4,5,5-tetramethyl-2-phenyl-1,3,2-dioxaborolane 1,3,2-Dioxaborolane,4,4,5,5-tetraMethyl-2-phenyl- cyclic tetramethylethylene ester benzeneboronic acid (4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzene (4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzene, 2-Phenyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
|
CAS | 24388-23-6
|
InChI | InChI=1/C12H17BO2/c1-11(2)12(3,4)15-13(14-11)10-8-6-5-7-9-10/h5-9H,1-4H3 |
InChIKey | KKLCYBZPQDOFQK-UHFFFAOYSA-N |
(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZENE - Physico-chemical Properties
Molecular Formula | C12H17BO2
|
Molar Mass | 204.07 |
Density | 0.99±0.1 g/cm3(Predicted) |
Melting Point | 27-31°C(lit.) |
Boling Point | 130°C/20mmHg(lit.) |
Flash Point | 225°F |
Vapor Presure | 0.00586mmHg at 25°C |
Appearance | powder to lump |
Color | White to Almost white |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.49 |
(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZENE - Risk and Safety
Risk Codes | R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
WGK Germany | 3 |
HS Code | 29319090 |
Hazard Note | Irritant |
(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZENE - Introduction
(4,4, 5,5-tetramethyl-1, 3,2-dioxaborolan-2-yl) benzene((4,4, 5,5-tetramethyl-1, 3,2-dioxaborolan-2-yl) benzene) is an organic compound, its molecular formula is C14H19BO2.
The compound has the following properties:
-Appearance: Colorless solid
-Solubility: Soluble in organic solvents such as chloroform, ether, dichloromethane
-Melting Point: about 80-82 ℃
-Stability: Insoluble in water, but may hydrolyze in a humid environment
The main use of this substance is as a reagent and catalyst in organic synthesis. It is commonly used in platinum-catalyzed Suzuki coupling reactions for the synthesis of different types of organic compounds, such as heterocyclic compounds and drug molecules.
A common method for preparing (4,4, 5,5-tetramethyl-1, 3,2-dioxaborolan-2-yl)benzene is to react hydrogenated tetramethyldiborane with bromobenzene. The specific reaction conditions can be adjusted according to the experimental requirements.
When using and handling (4,4, 5,5-tetramethyl-1, 3,2-dioxaborolan-2-yl)benzene, you need to pay attention to the following safety information:
-Wear appropriate protective equipment, such as gloves and glasses, for laboratory operations.
-Avoid direct contact with skin and eyes. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
-Keep away from combustibles and high-temperature fire sources to avoid contact with fire sources.
-storage should be sealed in a dry, cool place.
Last Update:2024-04-09 19:05:48