(4-BroMothien-2-yl)Methanol - Names and Identifiers
(4-BroMothien-2-yl)Methanol - Physico-chemical Properties
Molecular Formula | C5H5BrOS
|
Molar Mass | 193.06 |
Density | 1.772±0.06 g/cm3(Predicted) |
Melting Point | 30 °C |
Boling Point | 271.5±25.0 °C(Predicted) |
Flash Point | 117.994°C |
Solubility | soluble in Methanol |
Vapor Presure | 0.003mmHg at 25°C |
Appearance | powder to lump |
Color | White to Orange to Green |
pKa | 13.50±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | 1.631 |
(4-BroMothien-2-yl)Methanol - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 - Irritating to eyes, respiratory system and skin.
R41 - Risk of serious damage to eyes
R22 - Harmful if swallowed
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S39 - Wear eye / face protection.
|
(4-BroMothien-2-yl)Methanol - Introduction
(4-bromo-2-thienyl)methanol is an organic compound with the chemical formula C6H6Br2OS. The following is a description of its nature, use, preparation and safety information:
Nature:
(4-bromo-2-thienyl)methanol is a solid compound with light yellow crystal morphology. It is soluble in some organic solvents such as methanol and dimethyl sulfoxide at room temperature. It has a melting point of about 66-69°C.
Use:
(4-bromo-2-thienyl)methanol is a reagent commonly used in organic synthesis. It can be used as raw materials or intermediates in organic synthesis, such as synthetic drugs, pesticides and organic chemicals. Because it contains thiophene ring and bromine substituent, it has high reactivity and can participate in a series of chemical reactions, such as nucleophilic substitution, alcohol etherification reaction, etc.
Preparation Method:
(4-bromo-2-thienyl)methanol can be obtained by reacting 2-thiophenecarboxaldehyde with hydrogen bromide. The specific reaction steps are as follows:
First, dissolving 2-thiophenecarboxaldehyde in an appropriate solvent;
Then, hydrogen bromide is added dropwise and reacted at an appropriate temperature;
After the reaction is completed, the product is obtained through steps such as filtrate and crystallization.
Safety Information:
(4-bromo-2-thienyl)methanol is stable at room temperature, but at high temperatures or when encountering strong oxidants, dangerous chemical reactions may occur and require careful handling. For the handling, use and storage of chemicals, relevant safe operating procedures should be followed and appropriate protective equipment should be worn. In addition, care should be taken to avoid contact with skin, eyes and inhalation of its vapors. In case of accidental contact, please immediately perform physical flushing and seek medical help.
Last Update:2024-04-09 21:04:16