(4-NITRO-PYRAZOL-1-YL)-METHANOL
(4-Nitro-1H-pyrazol-1-yl)methanol
CAS: 1001518-99-5
Molecular Formula: C4H5N3O3
(4-NITRO-PYRAZOL-1-YL)-METHANOL - Names and Identifiers
(4-NITRO-PYRAZOL-1-YL)-METHANOL - Physico-chemical Properties
| Molecular Formula | C4H5N3O3 |
| Molar Mass | 143.1 |
| Storage Condition | Room Temprature |
| Sensitive | IRRITANT |
| MDL | MFCD05667115 |
(4-NITRO-PYRAZOL-1-YL)-METHANOL - Risk and Safety
| Hazard Class | IRRITANT |
(4-NITRO-PYRAZOL-1-YL)-METHANOL - Introduction
(a) methanol, also known as 4-nitro-1H-pyrazole-1-methanol, is an organic compound. The following is a detailed description of its nature, use, preparation and safety information:
Nature:
(.) methanol is a white to slightly yellow solid that is stable at room temperature. It has high temperature stability and is soluble in many organic solvents, such as ethanol, dimethylformamide and dichloromethane.
Use:
(br>) methanol is a synthetic intermediate, widely used in pesticides, drugs and dyes and other fields. It can be used as a substrate for the synthesis of novel organic synthesis reactions and has important chemical activities.
Preparation Method:
The preparation of methanol is usually achieved by the following steps:
1. One-step hydrolysis after the loss of maleimide to prepare 2-propyl amino -3,5-dimethyl pyrazine.
2. Convert 2-propylamino -3, 5-dimethylpyrazine to 2-propylamino -3, 5-dimethylpyridine in ethanol.
3. Dissolve 2-propylamino-3, 5-dimethylpyridine in anhydrous ethanol, then react with nitric acid, and reduce it by sodium hydroxide at low temperature to obtain the target product (B) methanol.
Safety Information:
(.) Follow basic laboratory safety procedures when using and storing methanol. It may be irritating and toxic to humans, so you should wear appropriate protective equipment, such as laboratory gloves and goggles. At the same time, avoid contact with skin, eyes and respiratory tract, and maintain good ventilation conditions. Such as accidental contact or ingestion, should promptly seek medical attention. Store and handle the substance properly to avoid ignition and sparks.
Nature:
(.) methanol is a white to slightly yellow solid that is stable at room temperature. It has high temperature stability and is soluble in many organic solvents, such as ethanol, dimethylformamide and dichloromethane.
Use:
(br>) methanol is a synthetic intermediate, widely used in pesticides, drugs and dyes and other fields. It can be used as a substrate for the synthesis of novel organic synthesis reactions and has important chemical activities.
Preparation Method:
The preparation of methanol is usually achieved by the following steps:
1. One-step hydrolysis after the loss of maleimide to prepare 2-propyl amino -3,5-dimethyl pyrazine.
2. Convert 2-propylamino -3, 5-dimethylpyrazine to 2-propylamino -3, 5-dimethylpyridine in ethanol.
3. Dissolve 2-propylamino-3, 5-dimethylpyridine in anhydrous ethanol, then react with nitric acid, and reduce it by sodium hydroxide at low temperature to obtain the target product (B) methanol.
Safety Information:
(.) Follow basic laboratory safety procedures when using and storing methanol. It may be irritating and toxic to humans, so you should wear appropriate protective equipment, such as laboratory gloves and goggles. At the same time, avoid contact with skin, eyes and respiratory tract, and maintain good ventilation conditions. Such as accidental contact or ingestion, should promptly seek medical attention. Store and handle the substance properly to avoid ignition and sparks.
Last Update：2024-04-09 21:11:58
