(4S)-4-Fluoro-D-proline

(4S)-4-Fluoro-D-proline - Names and Identifiers

Name	(2R,4S)-4-fluoropyrrolidine-2-carboxylic acid
Synonyms	(4S)-4-Fluor-D-prolin (4S)-4-Fluoro-D-proline trans-4-Fluoro-D-proline (2R,4S)-4-fluoro-2-proline D-Proline, 4-fluoro-, (4S)- D-proline, 4-fluoro-, (4S)- (2R,4S)-4-fluoropyrrolidinium-2-carboxylate (2R,4S)-4-Fluoro-2-pyrrolidinecarboxylic acid (2R,4S)-4-fluoropyrrolidine-2-carboxylic acid (2R,4S)-4-fluoropyrrolidine-2-carboxylic acid hydrochloride
CAS	131176-02-8
InChI	InChI=1/C5H8FNO2/c6-3-1-4(5(8)9)7-2-3/h3-4,7H,1-2H2,(H,8,9)/t3-,4+/m0/s1

(4S)-4-Fluoro-D-proline - Physico-chemical Properties

Molecular Formula	C5H8FNO2
Molar Mass	133.12
Density	1.3g/cm³
Boling Point	265.1°C at 760 mmHg
Flash Point	114.1°C
Vapor Presure	0.00271mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.472

(4S)-4-Fluoro-D-proline - Introduction

(2R,4S)-4-fluoropyrrolidine-2-carboxylic acid is an organic compound with the formula C6H7FO2, which is a white crystalline solid.

The following is a description of its nature, use, method and safety information:

Nature:
- (2R,4S)-4-fluoropyrrolidine-2-carboxylic acid has high thermal stability and solubility.
-It is stable at room temperature and not easy to decompose, but it can thermally decompose at high temperatures.
-It can be dissolved in water, alcohols and other organic solvents.

Use:
- (2R,4S)-4-fluoropyrrolidine-2-carboxylic acid can be used as an intermediate in drug synthesis, especially for the synthesis of amino acids and other organic compounds.
-It can also be used as a drug raw material in the pharmaceutical field, such as anti-epileptic drugs and anti-tumor drugs.

Preparation Method:
The preparation method of- (2R,4S)-4-fluoropyrrolidine-2-carboxylic acid is usually obtained by asymmetric synthesis. One of the common methods is to use enzyme catalysis or chiral ligands to catalyze the pseudo photosynthetic enzyme.

Safety Information:
-Due to the irritation and possible toxicity of compounds, safety measures must be taken during handling and use. Wear appropriate protective equipment such as gloves, goggles and lab coats.
-When storing and transporting, keep it away from fire and other flammable materials.
-Safety data sheets and instructions provided by the manufacturer should be strictly followed.
-When using this compound, good ventilation and reasonable operation methods should be carried out to avoid inhalation or skin contact. If the compound is accidentally inhaled or comes into contact with skin, wash it immediately and seek medical help.

Last Update：2024-04-09 21:04:16