(5S)-5-(chloromethyl)-1,3-oxazolidin-2-one

(5S)-5-(chloromethyl)-1,3-oxazolidin-2-one - Names and Identifiers

Name	5-Chloromethyl-2-oxazolidinone
Synonyms	NSC 111158 TIMTEC-BB SBB004204 5-Chlormethyloxazolidin-2-on 5-Chloromethyl-2-oxazolidone 5-chloromethyloxazolidin-2-one 5-Chloromethyloxazolidin-2-one 5-Chloromethyl-2-oxazolidinone 5-CHLOROMETHYL-2-OXAZOLIDINONE 5-(Chloromethyl)-1,3-oxazolidin-2-one 5-(chloromethyl)-1,3-oxazolidin-2-one (5S)-5-(chloromethyl)-1,3-oxazolidin-2-one (5R)-5-(chloromethyl)-1,3-oxazolidin-2-one
CAS	22625-57-6
EINECS	245-137-9
InChI	InChI=1/C4H6ClNO2/c5-1-3-2-6-4(7)8-3/h3H,1-2H2,(H,6,7)/t3-/m1/s1

(5S)-5-(chloromethyl)-1,3-oxazolidin-2-one - Physico-chemical Properties

Molecular Formula	C4H6ClNO2
Molar Mass	135.55
Density	1.2994 (rough estimate)
Melting Point	102-104°C(lit.)
Boling Point	382.8±11.0 °C(Predicted)
Flash Point	185.3°C
Vapor Presure	4.6E-06mmHg at 25°C
pKa	12.09±0.40(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.5500 (estimate)
MDL	MFCD00005269

(5S)-5-(chloromethyl)-1,3-oxazolidin-2-one - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	24/25 - Avoid contact with skin and eyes.
UN IDs	UN 2811 6.1 / PGIII
WGK Germany	3
HS Code	29349990

(5S)-5-(chloromethyl)-1,3-oxazolidin-2-one - Introduction

It is an organic compound with the chemical formula C5H8ClNO2. The following is a description of its nature, use, preparation and safety information:

1. Nature:
-Appearance: White crystalline solid.
-Solubility: It can be dissolved in water and some organic solvents.
-Melting point: Its melting point is about 78-81°C.
-Stability: It is a stable compound, but it may decompose under high temperature, light or oxidizing conditions.

2. Use:
-is an important organic synthesis intermediate, often used in the synthesis of other organic compounds.
-It can be used as a precursor for antibiotics (such as mitochondrial inhibitors).
-It can also be used to prepare other biologically active compounds, such as pesticides and drugs.

3. Preparation method:
-or can be prepared by chloromethylating 2-oxazolidinone. As a specific production method, 2-oxazolidinone can be reacted with a chloromethanylation reagent such as chloromethylsilver iodide to produce the target product under appropriate conditions. The reaction process requires attention to operational safety and waste disposal.

4. Safety Information:
-It may have a certain irritating effect on the human body, and it is recommended to wear appropriate protective measures during use, such as laboratory gloves and goggles.
-Avoid contact with eyes, skin and mouth. In case of contact, rinse immediately with plenty of water and seek medical help.
-Avoid high temperatures, ignition sources and open flames during operation and storage.
-Please handle and dispose of waste in accordance with relevant regulations.

Last Update：2024-04-09 19:05:48