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(5r-(5-alpha,6-alpha(r*)))-nomethyl)amino)ethyl)thio)-7-oxo

Imipenem

CAS: 64221-86-9

Molecular Formula: C12H17N3O4S

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(5r-(5-alpha,6-alpha(r*)))-nomethyl)amino)ethyl)thio)-7-oxo - Names and Identifiers

Name Imipenem
Synonyms mk-787
Imipenem
imipemide
Imipenem(MK-0787)
(5r-(5-alpha,6-alpha(r*)))-nomethyl)amino)ethyl)thio)-7-oxo
1-azabicyclo(3.2.0)hept-2-ene-2-carboxylicacid,6-(1-hydroxyethyl)-3-((2-((imi
2-[1,3-dioxo-1-[(2-oxo-1,3-dihydrobenzimidazol-5-yl)amino]butan-2-yl]azobenzene-1,4-dicarboxylic acid dimethyl ester
(5R,6S)-6-[(1R)-1-hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
(5R,6S)-3-[(2-{[(E)-aminomethylidene]amino}ethyl)sulfanyl]-6-[(1S)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
[5R-[5alpha, 6alpha(R*)]]-6-(1-Hydroxyethyl)-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
(5R,6S)-3-[(2-{[(E)-aminomethylidene]amino}ethyl)sulfanyl]-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
[5R-[5alpha, 6alpha(R*)]]-6-(1-Hydroxyethyl)-3- [[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
CAS 64221-86-9
EINECS 264-734-5
InChI InChI=1/C12H17N3O4S/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19)/t6-,7-,9-/m1/s1

(5r-(5-alpha,6-alpha(r*)))-nomethyl)amino)ethyl)thio)-7-oxo - Physico-chemical Properties

Molecular FormulaC12H17N3O4S
Molar Mass299.35
Density1.62±0.1 g/cm3(Predicted)
Melting Point106-111 C
Boling Point530.2±60.0 °C(Predicted)
Flash Point296.9°C
Solubility Sparingly soluble in water, slightly soluble in methanol.
Vapor Presure3.11E-15mmHg at 25°C
pKa4.29±0.40(Predicted)
Storage ConditionKeep in dark place,Sealed in dry,Store in freezer, under -20°C
Refractive Index1.721
MDLMFCD09753321

(5r-(5-alpha,6-alpha(r*)))-nomethyl)amino)ethyl)thio)-7-oxo - Risk and Safety

Hazard SymbolsXi - Irritant
Irritant
Risk Codes36/37/38 - Irritating to eyes, respiratory system and skin.
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S27 - Take off immediately all contaminated clothing.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
HS Code29419000

(5r-(5-alpha,6-alpha(r*)))-nomethyl)amino)ethyl)thio)-7-oxo - Reference

Reference
Show more
1. He Wenxiu, Lu Enhao, Sha Xianyi. Stability evaluation of different infusion ratios of imipenem cilastatin sodium for injection [J]. Chinese Pharmacoeconomics, 202015 Vol. 7, 60-66 pages, 2020.
2. Wu Lingling, Wei Dun can, Chen Hao Hao. Effect of berberine hydrochloride combined with imipenem on in vitro antibacterial activity of carbapenem-resistant Pseudomonas aeruginosa [J]. China medical science, 2018,8(17):69-72.
3. Shi Qingxin, Lu Xiaoping, Yu Qingfeng, Yang Yang. In vitro drug sensitivity test of carbapenem-resistant Pseudomonas aeruginosa induced by berberine hydrochloride combined with imipenem [J]. Modern doctor of China, 2017,55(01):114-117.
4. Jia Cheng et al. [IF = 4.034]. "Antimicrobial resistance profiles of 5 common bovine mstitis pathogens in large Chinese dairy herds." J Dairy Sci. Mar 2019; 102:2416
5. [IF = 14.919] Qing Guangchao et al."Thermo-responsive triple-function nanotransporter for efficient chemo-photothermal therapy of multidrug-resistant bacterial infection. Nat Commun. 2019 Sep;10(1):1-12
6. [IF=3.743] Guorong Zhang et al."Treatment with andrographolide sulfonate provides additional benefits to imipenem in a mouse model of Klebsiella pneumoniae pneumonia."Biomed Pharmacother. 2019 Sep;117:109065
(5r-(5-alpha,6-alpha(r*)))-nomethyl)amino)ethyl)thio)-7-oxo
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Shanghai Yuanye Bio-Technology Co., Ltd.
Featured ProductsSpot supply
Product Name: Imipenem Visit Supplier Webpage Request for quotation
CAS: 64221-86-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Wechat: 18301782025
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: Imipenem Request for quotation
CAS: 64221-86-9
Tel: 0086-551-65418684
Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 0086 189 4982 3763
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(5r-(5-alpha,6-alpha(r*)))-nomethyl)amino)ethyl)thio)-7-oxo
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