(6R)-FR054
(6R)-FR054
CAS: 10378-06-0
Molecular Formula: C14H19NO8
(6R)-FR054 - Names and Identifiers
(6R)-FR054 - Physico-chemical Properties
| Molecular Formula | C14H19NO8 |
| Molar Mass | 329.3 |
| Density | 1.45±0.1 g/cm3(Predicted) |
| Boling Point | 416.7±45.0 °C(Predicted) |
| Solubility | Soluble in DMSO |
| Appearance | Oil |
| Color | Light Yellow to Yellow Thick |
| pKa | 3.69±0.70(Predicted) |
| Storage Condition | 4°C, Inert atmosphere |
| Use | (6R)-FR054 is an active isomer of FR054. FR054 is an inhibitor of the HBP enzyme PGM3, with a remarkable anti-breast cancer effect. FR054induces endoplasmic reticulum (ER) stress and a ROS-dependent apoptosis |
(6R)-FR054 - Reference
| Reference Show more | 1: Ricciardiello F, Votta G, Palorini R, Raccagni I, Brunelli L, Paiotta A, Tinelli F, D'Orazio G, Valtorta S, De Gioia L, Pastorelli R, Moresco RM, La Ferla B, Chiaradonna F. Inhibition of the Hexosamine Biosynthetic Pathway by targeting PGM3 causes breast cancer growth arrest and apoptosis. Cell Death Dis. 2018 Mar 7;9(3):377. doi: 10.1038/s41419-018-0405-4. PubMed PMID: 29515119; PubMed Central PMCID: PMC5841296. |
(6R)-FR054 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.037 ml | 15.184 ml | 30.367 ml |
| 5 mM | 0.607 ml | 3.037 ml | 6.073 ml |
| 10 mM | 0.304 ml | 1.518 ml | 3.037 ml |
| 5 mM | 0.061 ml | 0.304 ml | 0.607 ml |
Last Update：2024-01-02 23:10:35
(6R)-FR054 - Reference Information
| biological activity | (6R)-FR054 is an active isomer of fr054. FR054 is an inhibitor of the HBP enzyme PGM3 and has significant anti-breast cancer activity. FR054 can induce endoplasmic reticulum stress and ROS-dependent apoptosis. |
Last Update：2024-04-09 21:54:55
Supplier List
Spot supply
Product Name: (6R)-FR054 Visit Supplier Webpage Request for quotationCAS: 10378-06-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: (6R)-FR054 Visit Supplier Webpage Request for quotationCAS: 10378-06-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History