(9H-fluoren-9-yl)methyl3-oxopiperidine-1-carboxylate
(9H-fluoren-9-yl)methyl3-oxopiperidine-1-carboxylate
CAS: 672310-11-1
Molecular Formula: C20H19NO3
(9H-fluoren-9-yl)methyl3-oxopiperidine-1-carboxylate - Names and Identifiers
| Name | (9H-fluoren-9-yl)methyl3-oxopiperidine-1-carboxylate |
| Synonyms | N-FMoc-3-piperidone N-Fmoc-3-Piperidinone 1-n-fmoc-3-piperidone1-FMOC-3-piperidinone 9H-Fluoren-9-ylmethyl 3-oxopiperidine-1-carboxylate (9H-fluoren-9-yl)methyl3-oxopiperidine-1-carboxylate (9H-FLUOREN-9-YL)METHYL 3-OXOPIPERIDINE-2-CARBOXYLATE 3-Oxo-1-piperidinecarboxylic acid 9H-fluoren-9-ylmethyl ester 1-Piperidinecarboxylic acid, 3-oxo-, 9H-fluoren-9-ylmethyl ester |
| CAS | 672310-11-1 |
| InChI | InChI=1/C20H19NO3/c22-14-6-5-11-21(12-14)20(23)24-13-19-17-9-3-1-7-15(17)16-8-2-4-10-18(16)19/h1-4,7-10,19H,5-6,11-13H2 |
(9H-fluoren-9-yl)methyl3-oxopiperidine-1-carboxylate - Physico-chemical Properties
| Molecular Formula | C20H19NO3 |
| Molar Mass | 321.37 |
| Density | 1.255g/cm3 |
| Melting Point | 90-96℃ |
| Boling Point | 510.4°C at 760 mmHg |
| Flash Point | 262.5°C |
| Water Solubility | Slightly soluble in water. |
| Vapor Presure | 1.55E-10mmHg at 25°C |
| Storage Condition | Room Temprature |
| Refractive Index | 1.616 |
(9H-fluoren-9-yl)methyl3-oxopiperidine-1-carboxylate - Risk and Safety
| Hazard Symbols | N - Dangerous for the environment |
| Risk Codes | 50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
| Safety Description | S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| UN IDs | UN 3077 9 / PGIII |
| WGK Germany | 3 |
| Hazard Class | 9 |
(9H-fluoren-9-yl)methyl3-oxopiperidine-1-carboxylate - Introduction
(9H-fluoren-9-yl)methyl3-oxopiperidine-1-carboxylate((9H-fluoren-9-yl)methyl3-oxopiperidine-1-carboxylate) is an organic compound with the following properties, uses, preparation and safety information:
Nature:
-Appearance: White or off-white solid
-Molecular formula: C23H22N2O3
-Molecular weight: 374.43g/mol
-Melting point: 156-158°C
-Solubility: Slightly soluble in water, soluble in common organic solvents such as ethanol, chloroform and dimethylformamide
Use:
- (9H-fluoren-9-yl)methyl3-oxopiperidine-1-carboxylate is an important intermediate in organic synthesis.
-It is widely used in the field of medicine, can be used for the synthesis of anti-cancer drugs, anti-inflammatory drugs and analgesic drugs.
-In the field of pesticides, it can be used for the synthesis of pesticides, such as insecticides and fungicides.
Preparation Method:
The- (9H-fluoren-9-yl)methyl3-oxopiperidine-1-carboxylate can be prepared by a multi-step synthesis method.
-One of the common preparation methods is to first synthesize the fluorene methyl chloroformate compound, and then condense with 3-piperidone to obtain the final product.
Safety Information:
- (9H-fluoren-9-yl)methyl3-oxopiperidine-1-carboxylate is a chemical substance, which needs to comply with relevant safety operation regulations when used.
-Personal protective equipment such as lab gloves, goggles and protective clothing should be worn during handling and use.
-Avoid inhalation, ingestion or contact with skin and eyes.
-During storage and handling, avoid contact with oxidants and strong acids to avoid dangerous reactions.
-In case of accidental contact or inhalation, seek medical attention immediately.
Nature:
-Appearance: White or off-white solid
-Molecular formula: C23H22N2O3
-Molecular weight: 374.43g/mol
-Melting point: 156-158°C
-Solubility: Slightly soluble in water, soluble in common organic solvents such as ethanol, chloroform and dimethylformamide
Use:
- (9H-fluoren-9-yl)methyl3-oxopiperidine-1-carboxylate is an important intermediate in organic synthesis.
-It is widely used in the field of medicine, can be used for the synthesis of anti-cancer drugs, anti-inflammatory drugs and analgesic drugs.
-In the field of pesticides, it can be used for the synthesis of pesticides, such as insecticides and fungicides.
Preparation Method:
The- (9H-fluoren-9-yl)methyl3-oxopiperidine-1-carboxylate can be prepared by a multi-step synthesis method.
-One of the common preparation methods is to first synthesize the fluorene methyl chloroformate compound, and then condense with 3-piperidone to obtain the final product.
Safety Information:
- (9H-fluoren-9-yl)methyl3-oxopiperidine-1-carboxylate is a chemical substance, which needs to comply with relevant safety operation regulations when used.
-Personal protective equipment such as lab gloves, goggles and protective clothing should be worn during handling and use.
-Avoid inhalation, ingestion or contact with skin and eyes.
-During storage and handling, avoid contact with oxidants and strong acids to avoid dangerous reactions.
-In case of accidental contact or inhalation, seek medical attention immediately.
Last Update：2024-04-09 02:00:47
