(D3-NNK)

(D3-NNK) - Names and Identifiers

Name	4-(Methylnitrosamino)-1-(3-pyridyl-d4)-1-butanone (1.0 mg/mL in Acetonitrile)
Synonyms	NNK-D3 NNK-d4 (D3-NNK) N-Nitrosonornicotine-ketone D4 (pyridyl D4) 4-(Methylnitrosamino)-1-(3-pyridyl-d4)-1-butanone 4-(METHYL-D3-NITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE 4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl-d4)-1-butanone 4-[(N-Methyl-d3)-N-nitrosamino]-1-(3-pyridyl)-1-butanone
CAS	764661-24-7

(D3-NNK) - Physico-chemical Properties

Molecular Formula	C10H9D4N3O2
Molar Mass	211.26
Melting Point	60-62°C
Storage Condition	Amber vial, -20°C Freezer

(D3-NNK) - Risk and Safety

Risk Codes	R11 - Highly Flammable R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R41 - Risk of serious damage to eyes R38 - Irritating to the skin
Safety Description	S15 - Keep away from heat. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S46 - If swallowed, seek medical advice immediately and show this container or label. S27/28 -
UN IDs	UN2811 6.1/PG 3
HS Code	28459000

(D3-NNK) - Introduction

4-(Methylnitrosamino)-1-(3-pyridyl-d4)-1-butanone (1.0 mg/ml in acetonitril)(4-(Methylnitrosamino)-1-(3-pyridyl-d4)-1-butanone), the chemical formula is C11H12D4N2O2, which is an organic compound.

The compound is a kind of nitrosamine compounds, with strong carcinogenicity. It is a common component in filter-containing cigarettes and is considered to be one of the important carcinogens that cause smoking-related diseases. It has a strong mutagenic and carcinogenic effect on the DNA of the human body, so it is widely used in the research field of various cancers.

The preparation method of 4-(Methylnitrosamino)-1-(3-pyridyl-d4)-1-butanone (1.0 mg/ml in acetonitril) is relatively complicated and generally needs to be synthesized through multi-step reactions. First, it is necessary to carry out the reaction using synthetic raw materials and reagents, and finally obtain the target product through a series of reaction steps. This process requires chemical laboratory equipment and expertise, as well as strict control of reaction conditions and safe operation.

Regarding safety information, because the compound has a strong carcinogenic effect and is toxic to the human body, strict safety operation measures are usually required when used in the laboratory. Users are required to wear appropriate protective equipment such as glasses, gloves and lab clothes. At the same time, pay attention to avoid contact with skin, eyes and mouth, and maintain good ventilation conditions. When using and handling the compound, it is necessary to strictly follow the relevant safety procedures and disposal methods.

To sum up, 4-(Methylnitrosamino)-1-(3-pyridyl-d4)-1-butanone (1.0 mg/ml in acetonitril) is an organic compound with strong carcinogenic effect, it is often used in the study of smoking-related diseases and cancer. Its preparation method is more complex, the use of strict compliance with safety procedures.

Last Update：2024-04-10 22:29:15