(E)-3-(Dimethylamino)-1-(pyridin-2-yl)prop-2-en-1-one

(E)-3-(Dimethylamino)-1-(pyridin-2-yl)prop-2-en-1-one - Names and Identifiers

Name	2-Propen-1-one, 3-(dimethylamino)-1-(2-pyridinyl)-, (E)-
Synonyms	(2E)-3-(DiMethylaMino)-1-(2-pyridyl)-2-propen-1-one (E)-3-(Dimethylamino)-1-(pyridin-2-yl)prop-2-en-1-one (E)-3-(diMethylaMino)-1-(pyridin-2-yl)prop-2-en-1-one 3-(N,N-dimethylamino)-1-(pyridin-2-yl)-2-propen-1-one 2-Propen-1-one, 3-(dimethylamino)-1-(2-pyridinyl)-, (E)- 2-Propen-1-one, 3-(dimethylamino)-1-(2-pyridinyl)-, (2E)-
CAS	123367-25-9

(E)-3-(Dimethylamino)-1-(pyridin-2-yl)prop-2-en-1-one - Physico-chemical Properties

Molecular Formula	C10H12N2O
Molar Mass	176.22
Density	1.070±0.06 g/cm3(Predicted)
Melting Point	110 °C(Solv: ethyl acetate (141-78-6))
Boling Point	281.4±36.0 °C(Predicted)
pKa	4.85±0.70(Predicted)
Storage Condition	2-8°C

(E)-3-(Dimethylamino)-1-(pyridin-2-yl)prop-2-en-1-one - Introduction

(E)-3-(Dimethylamino)-1-(2-pyridyl)-2-propen-1-one, also known as DMAP, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: DMAP is a white crystalline solid.
-Solubility: DMAP can be dissolved in common organic solvents, such as methanol, dimethylformamide, etc.
-Melting point: The melting point of DMAP is 88-90°C.
-Boiling Point: DMAP has no definite boiling point value at atmospheric pressure.
-Chemical properties: DMAP is a basic compound, which can react with acids to generate salts, and can also be used as a catalyst to participate in organic reactions.

Use:
-Catalyst: DMAP is often used as a catalyst in organic synthesis, especially in esterification, etherification and other reactions.
-Intermediate: As an intermediate, DMAP can participate in a series of organic synthesis reactions, such as the synthesis of drugs and dyes.

Preparation Method:
DMAP can be prepared by reacting dimethylamine and pyridine iodide under basic conditions. It can also be prepared by reacting 3-amino-2-propenone and pyridine in N,N-dimethylformamide.

Safety Information:
- DMAP is irritating to the skin and eyes. After contact, rinse with water immediately and seek medical attention.
- DMAP has a certain toxicity and should be kept away from children and used in a well-ventilated place.
-During use, wear protective glasses and gloves to avoid inhaling its dust or vapor.
- DMAP should be stored in a dry, cool, ventilated place, and away from sources of fire.

Last Update：2024-04-09 02:00:41