(E)-N,N-Dimethyl-3-(pyridin-4-yl)acrylamide

(E)-N,N-Dimethyl-3-(pyridin-4-yl)acrylamide - Names and Identifiers

Name	2-Propen-1-one, 3-(dimethylamino)-1-(4-pyridinyl)-, (2E)-
Synonyms	(E)-N,N-Dimethyl-3-(pyridin-4-yl)acrylamide 3-(diMethylaMino)-1-(pyridin-4-yl)prop-2-en-1-o 3-(diMethylaMino)-1-(pyridin-4-yl)prop-2-en-1-one 2-Propen-1-one, 3-(dimethylamino)-1-(4-pyridinyl)-, (2E)-
CAS	123367-27-1

(E)-N,N-Dimethyl-3-(pyridin-4-yl)acrylamide - Physico-chemical Properties

Molecular Formula	C10H12N2O
Molar Mass	176.22
Density	1.070±0.06 g/cm3(Predicted)
Melting Point	114℃ (ethyl acetate isopropyl ether )
Boling Point	281.4±36.0 °C(Predicted)
pKa	4.47±0.70(Predicted)
Storage Condition	Sealed in dry,Room Temperature

(E)-N,N-Dimethyl-3-(pyridin-4-yl)acrylamide - Introduction

3-(Dimethylamino)-1-(4-pyridyl)-2-propen-1-one, also known as DMAP, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: DMAP is a colorless crystalline solid.
-Solubility: It is insoluble in water, but can be dissolved in many organic solvents, such as alcohols, ethers and ketones.
-Melting point: The melting point of DMAP is about 101°C.
-Molecular structure: It consists of a acrylone group and a dimethylamino group containing a pyridine group.

Use:
-Catalyst: DMAP is an effective catalyst for organic chemical reactions, especially in organic synthesis. It can participate in the reaction of amide, ester and acid chloride, and promote aminocarbonylation reaction, amination reaction and imine reaction.

Preparation Method:
- DMAP can be prepared by using formaldehyde, formic acid and dimethylamine as raw materials and synthesized through a series of chemical steps. The specific preparation method needs to be carried out in a suitable laboratory environment and conditions.

Safety Information:
- DMAM is a chemical. When used, follow correct laboratory operating procedures and use necessary personal protective equipment.
-Avoid inhalation, contact with skin and ingestion during use, and avoid dust and mist.
-If a large amount of DMAP is exposed to the outside, flush the affected area immediately with plenty of water and seek medical attention immediately.

Please note that DMAP is a chemical and should be used under appropriate laboratory conditions after understanding and familiarizing itself with its proper use, handling, and safe use information.

Last Update：2024-04-09 15:17:51