(E)-N-Methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide
AFN-1252
CAS: 620175-39-5
Molecular Formula: C22H21N3O3
(E)-N-Methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide - Names and Identifiers
(E)-N-Methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide - Physico-chemical Properties
| Molecular Formula | C22H21N3O3 |
| Molar Mass | 375.42 |
| Density | 1.28±0.1 g/cm3(Predicted) |
| Boling Point | 601.2±65.0 °C(Predicted) |
| Solubility | DMSO: 5.8 mg/mL(Need ultrasonic) |
| pKa | 3.60±0.20(Predicted) |
| Storage Condition | 2-8°C |
(E)-N-Methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.664 ml | 13.318 ml | 26.637 ml |
| 5 mM | 0.533 ml | 2.664 ml | 5.327 ml |
| 10 mM | 0.266 ml | 1.332 ml | 2.664 ml |
| 5 mM | 0.053 ml | 0.266 ml | 0.533 ml |
Last Update：2024-01-02 23:10:35
(E)-N-Methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide - Reference Information
| biological activity | AFN-1252(Debio 1452) is a highly potent inhibitor of FabI, which can inhibit Staphylococcus aureus. |
Last Update：2024-04-10 22:30:50
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CAS: 620175-39-5
Tel: 18301782025
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QQ: 3008007409
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CAS: 620175-39-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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