(HYDROXYMETHYL)CYCLOBUTANE
Hydroxymethylcyclobutane
CAS: 4415-82-1
Molecular Formula: C5H10O
(HYDROXYMETHYL)CYCLOBUTANE - Names and Identifiers
| Name | Hydroxymethylcyclobutane |
| Synonyms | CYCLOBUTYLMETHANOL cyclobutylcarbinol CYCLOBUTANECARBINOL RARECHEM AK ML 0579 CYCLOBUTANEMETHANOL cyclo butane methanol Hydroxymethylcyclobutane (HYDROXYMETHYL)CYCLOBUTANE Cyclobutylcarbinol~Hydroxymethylcyclobutane |
| CAS | 4415-82-1 |
| EINECS | 224-575-4 |
| InChI | InChI=1/C5H10O/c6-4-5-2-1-3-5/h5-6H,1-4H2 |
| InChIKey | WPOPOPFNZYPKAV-UHFFFAOYSA-N |
(HYDROXYMETHYL)CYCLOBUTANE - Physico-chemical Properties
| Molecular Formula | C5H10O |
| Molar Mass | 86.13 |
| Density | 0.913g/mLat 25°C(lit.) |
| Melting Point | 68.5 °C |
| Boling Point | 143-144°C(lit.) |
| Flash Point | 104°F |
| Water Solubility | immiscible |
| Vapor Presure | 2.14mmHg at 25°C |
| Appearance | Liquid |
| Color | Clear colorless |
| BRN | 2036027 |
| pKa | 15.26±0.10(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | n20/D 1.446(lit.) |
| Physical and Chemical Properties | Liquid. Boiling point 143-144 deg C, refractive index (nD25)1.4422. |
(HYDROXYMETHYL)CYCLOBUTANE - Risk and Safety
| Hazard Symbols | R10 - 易燃 |
| Risk Codes | 10 - Flammable |
| Safety Description | S16 - Keep away from sources of ignition. S24/25 - Avoid contact with skin and eyes. |
| UN IDs | UN 1987 3/PG 3 |
| WGK Germany | 3 |
| HS Code | 29061900 |
| Hazard Class | 3 |
| Packing Group | III |
(HYDROXYMETHYL)CYCLOBUTANE - Reference Information
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| uses | intermediates of analgesics such as butorphanol and nastorphine. |
| Production method | Use 1, 3-bromochloropropane and diethyl malonate to form cyclobutyl -1, 1-dicarboxylic acid under the action of sodium ethoxide diethyl ester, and then hydrolyze and decarboxylate to obtain cyclobutyl carboxylic acid, which is reduced to obtain the product. |
Last Update：2024-04-09 21:04:16
