(Piperidin-1-yl)(Piperidin-4-yl)methanone

(Piperidin-1-yl)(Piperidin-4-yl)methanone - Names and Identifiers

Name	1-(PIPERIDIN-4-YLCARBONYL)PIPERIDINE
Synonyms	ART-CHEM-BB B025011 PIPERIDINO(4-PIPERIDINYL)METHANONE 1-(PIPERIDIN-4-YLCARBONYL)PIPERIDINE PIPERIDIN-4-YL-PIPERIDIN-1-YL-METHANONE (Piperidin-1-yl)(Piperidin-4-yl)methanone 1-(piperidin-4-ylcarbonyl)piperidine 1HCl 1-(piperidin-4-ylcarbonyl)piperidine(SALTDATA,HCl)
CAS	63214-58-4

(Piperidin-1-yl)(Piperidin-4-yl)methanone - Physico-chemical Properties

Molecular Formula	C11H20N2O
Molar Mass	196.29
Density	1.047±0.06 g/cm3(Predicted)
Boling Point	350.5±35.0 °C(Predicted)
pKa	10.05±0.10(Predicted)
Storage Condition	Room Temprature

(Piperidin-1-yl)(Piperidin-4-yl)methanone - Risk and Safety

Hazard Class

IRRITANT

(Piperidin-1-yl)(Piperidin-4-yl)methanone - Upstream Downstream Industry

Raw Materials

Sodium hydroxide
Hydrochloric acid
Ethyl acetate
Dichloromethane
Sodium carbonate
Magnesium sulfate
Sodium chloride
Sodium bicarbonate
Acetonitrile
1,4-Dioxane
Di-tert-butyl dicarbonate
Piperidine
Isonipecotic acid
2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate
tert-butyl 4-(1-piperidinylcarbonyl)-1-piperidinecarboxylate
piperidin-1-yl(pyridin-4-yl)methanone
N-BOC-piperidine-4-carboxylic acid

(Piperidin-1-yl)(Piperidin-4-yl)methanone - Introduction

1-(PIPERIDIN-4-YLCARBONYL)PIPERIDINE is an organic compound with the molecular formula calloc halloc NO₂. The following is an introduction to its nature, use, preparation and safety information:

Nature:
1-(PIPERIDIN-4-YLCARBONYL)PIPERIDINE is a solid compound with the appearance of white to yellow crystals. It has a special odor, soluble in alcohols, ethers and ketones solvents, slightly soluble in water. It is a moderately toxic compound.

Use:
1-(PIPERIDIN-4-YLCARBONYL)PIPERIDINE is commonly used as an intermediate in organic synthesis. It can be used as an important structural unit in the synthesis of drugs for the synthesis of various biologically active compounds, such as drugs and pesticides. In addition, it can also be used as a catalyst for organic chemical reactions.

Method:
The preparation method of 1-(PIPERIDIN-4-YLCARBONYL)PIPERIDINE can be carried out by the following steps:
1. First, 4-piperidinecarboxylate is generated by the reaction of acid chloride and 4-piperidinecarboxylate.
2. Then, 4-piperidinecarboxylate was reacted with 4-piperidinecarbonyl chloride under base catalysis to obtain 1-(PIPERIDIN-4-YLCARBONYL)PIPERIDINE.

Safety Information:
1-(PIPERIDIN-4-YLCARBONYL)PIPERIDINE has certain toxicity and is a harmful compound to the human body. During use and operation, attention should be paid to protective measures. In case of contact with skin, eyes or respiratory system, rinse immediately with water and seek medical attention. During storage and handling, it must be kept away from heat and fire sources. In addition, the compound also has the risk of environmental pollution, and waste should be properly disposed of after use. In summary, the use of 1-(PIPERIDIN-4-YLCARBONYL)PIPERIDINE requires caution and must be handled in accordance with safe operating procedures.

Last Update：2024-04-09 21:01:54