(R)-(+)-3-HYDROXY-GAMMA-BUTYROLACTONE - Names and Identifiers
(R)-(+)-3-HYDROXY-GAMMA-BUTYROLACTONE - Physico-chemical Properties
Molecular Formula | C4H6O3
|
Molar Mass | 102.09 |
Density | 1.24 |
Boling Point | 98-100°C |
Flash Point | >110°C |
Solubility | Miscible with ethanol and chloroform. |
Vapor Presure | 5.42E-05mmHg at 25°C |
BRN | 3648447 |
pKa | 12.87±0.20(Predicted) |
Storage Condition | Inert atmosphere,2-8°C |
Refractive Index | 1.4655 |
MDL | MFCD00211248 |
(R)-(+)-3-HYDROXY-GAMMA-BUTYROLACTONE - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | R36/38 - Irritating to eyes and skin.
R41 - Risk of serious damage to eyes
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S39 - Wear eye / face protection.
|
HS Code | 29322985 |
(R)-(+)-3-HYDROXY-GAMMA-BUTYROLACTONE - Introduction
(R)-( )-beta-Hydroxy-gamma-butyrolactone is an organic compound with the chemical formula C4H6O3. It is a colorless liquid with a special smell. Its optical activity is mainly produced by the reaction of (R)-( )-2,3-butanediol and γ-caprolactone.
This compound has certain uses in the field of medicine. It can be used as an intermediate in the synthesis of drugs, and can also be used to prepare compounds with specific activities. In addition, it is also widely used in organic synthesis, catalytic reactions and chemical research.
The method of preparing (R)-( )-beta-Hydroxy-gamma-butyrolactone can be completed in two steps. First, (R)-( )-2,3-butanediol is esterified with an acidic catalyst to obtain (R)-( )-β-hydroxybutyric acid. Then, (R)-(+)-β-hydroxybutyric acid is converted to (R)-(+)-beta-Hydroxy-gamma-butyrolactone by a thermodynamically reversible conversion reaction.
From a safety point of view,(R)-( )-beta-Hydroxy-gamma-butyrolactone has certain toxicity. During use, care should be taken to prevent inhalation, swallowing or contact with skin and eyes. During operation, it is necessary to wear appropriate personal protective equipment, such as gloves and safety glasses. In addition, the compound should be stored in a cool, dry place and stored separately from flammable materials and oxidants. Disposal of waste shall be in accordance with local laws and regulations. Please read the safety information carefully and follow the corresponding operating procedures before use.
Last Update:2024-04-09 21:01:54