Molecular Formula | C17H19NO |
Molar Mass | 253.35 |
Density | 1.0078 (rough estimate) |
Melting Point | 77-80°C |
Boling Point | 396.54°C (rough estimate) |
Specific Rotation(α) | 59 º (589nm, c=3, MeOH 25 ºC) |
Flash Point | 133.3°C |
Vapor Presure | 1.67E-07mmHg at 25°C |
Appearance | White powder |
Color | white to off-white |
BRN | 4353363 |
pKa | 13.15±0.29(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Refractive Index | 58 ° (C=2, MeOH) |
MDL | MFCD00077754 |
Physical and Chemical Properties | Melting point 77-81°C specific rotation 59 ° (589nm, c = 3, MeOH 25°C) |
Use | It is used to prepare the corresponding oxazoborane, which can be used for the borane-mediated asymmetric reduction reaction of ketones. |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection |
WGK Germany | 3 |
FLUKA BRAND F CODES | 10-34 |
TSCA | No |
HS Code | 29221990 |
Use | (R)-( )-α, α-diphenyl-2-pyrrolidine methanol has been proven to have amphetamine-like effects and is used in recreational drugs. It is a new class of synthetic stimulants called piprado derivatives. It inhibits neurite growth in PC12 cells, which contributes to its neurotoxic effects. It is used as a reagent in the synthesis of the antidepressant (S)-duloxetine. It is used to prepare chiral Corey-Bakshi-Shibata catalysts for organic synthesis. It is used to prepare the corresponding oxazolobane, which can be used for the borane-mediated asymmetric reduction reaction of ketones. |
NIST chemical information | information provided by: webbook.nist.gov (external link) |