(R)-(-)-3-HYDROXYBUTYRONITRILE

(R)-(-)-3-HYDROXYBUTYRONITRILE - Names and Identifiers

Name	(R)-(-)-3-HYDROXYBUTYRONITRILE
Synonyms	(R)-3-Hydroxybutanenitrile (3R)-3-Hydroxybutanenitrile (3R)-3-hydroxybutanenitrile (R)-(-)-3-HYDROXYBUTYRONITRILE Butanenitrile, 3-hydroxy-, (3R)-
CAS	125103-95-9
InChI	InChI=1/C4H7NO/c1-4(6)2-3-5/h4,6H,2H2,1H3/t4-/m1/s1

(R)-(-)-3-HYDROXYBUTYRONITRILE - Physico-chemical Properties

Molecular Formula	C4H7NO
Molar Mass	85.1
Density	0.991
Boling Point	217℃
Flash Point	85℃
Solubility	DCM, Ethyl Acetate
Vapor Presure	0.0286mmHg at 25°C
pKa	13.89±0.20(Predicted)
Refractive Index	1.425

(R)-(-)-3-HYDROXYBUTYRONITRILE - Introduction

(R)-(-)-3-hydroxybutyronitrile has the molecular formula C4H9NO and has a molecular weight of 87.12g/mol. It is a colorless liquid with a pungent odor at room temperature. The following are some of the properties, uses, preparation and safety information of the compound:

Nature:
- (R)-(-)-3-hydroxybutyronitrile is chiral and can only exist in the form of the R-enantiomer.
-It can be dissolved in water and some organic solvents, such as ethanol and ether.

Use:
- (R)-(-)-3-hydroxybutyronitrile is an important intermediate in organic synthesis, which is commonly used in the preparation of pesticides, pharmaceuticals and dyes.
-It can play an important role as a catalyst and ligand in asymmetric synthesis.
-In chemical research, it is also used as a reference material for chiral analysis and chiral catalytic reactions.

Method:
- (R)-(-)-3-hydroxybutyronitrile can be prepared by a variety of methods. One of the common methods is the use of chloroacetyl cyanide in the presence of a base with enantioselective reaction.

Safety Information:
- (R)-(-)-3-hydroxybutyronitrile is an irritant substance and requires protective measures when in contact with skin, eyes or respiratory tract.
-During use and storage, maintain good ventilation conditions.
-Due to its chiral characteristics, its use must be strictly controlled to prevent problems caused by the mixing of enantiomers.

Follow appropriate laboratory safety practices and regulations when using or handling this compound. If you need further information, please consult a professional or refer to the relevant literature.

Last Update：2024-04-09 21:04:16