(R)-1-(4-tert-butylphenyl)ethanamine

(R)-1-(4-tert-butylphenyl)ethanamine - Names and Identifiers

Name	(R)-1-(4-tert-Butylphenyl)ethanamine
Synonyms	1-CHLOROINDANE (R)-1-(4-tert-Butylphenyl)ethanamine (R)-1-(4-tert-butylphenyl)ethanamine (R)-1-(4-tert-Butylphenyl)ethylamine (1R)-1-(4-tert-butylphenyl)ethan-1-amine Benzenemethanamine, 4-(1,1-dimethylethyl)-α-methyl-, (αR)- Benzenemethanamine, 4-(1,1-dimethylethyl)-a-methyl-, (aR)- Benzenemethanamine, 4-(1,1-dimethylethyl)-.alpha.-methyl-, (.alpha.R)-
CAS	511256-38-5

(R)-1-(4-tert-butylphenyl)ethanamine - Physico-chemical Properties

Molecular Formula	C12H19N
Molar Mass	177.29
Storage Condition	2-8°C

(R)-1-(4-tert-butylphenyl)ethanamine - Introduction

(R)-1-(4-tert-Butylphenyl)ethanamine is a chiral compound with the formula C12H19N. It is a white crystalline solid, soluble in organic solvents such as ethanol and dichloromethane. It has the structural basis of the natural amino acid isoleucine, has a chiral center, and there are two possible configurations:(R) and (S). The (R)-1-(4-tert-Butylphenyl)ethanamine is isoleucine in the (R) configuration.

(R)-1-(4-tert-Butylphenyl)ethanamine is mainly used for the preparation of chiral drugs and chiral inducers in chemical synthesis. The activity of many bioactive molecules or drugs depends on their chirality, so (R)-1-(4-tert-Butylphenyl)ethanamine has broad application prospects in drug research and synthesis.

The preparation of (R)-1-(4-tert-Butylphenyl)ethanamine can be obtained by an asymmetric synthesis method. One commonly used method is the electrochemical reduction of 4-tert-butylbenzaldehyde with ethylamine to give (R)-1-(4-tert-Butylphenyl)ethanamine.

Regarding safety information, due to the particularity of chiral drugs, care must be taken to prevent moisture and direct sunlight when handling and storing (R)-1-(4-tert-Butylphenyl)ethanamine. In addition, it should be stored in a sealed container and away from combustibles and oxidants. For any chemical, operators should follow safety regulations, wear suitable personal protective equipment, and avoid direct contact with skin and eyes. It should be ensured that it is operated under safe ventilation conditions and that inhalation of aerosols or dust is avoided. Consult and obtain detailed safety information from a regular chemical supplier if required.

Last Update：2024-04-09 20:52:54