(R)-1-Methyl-2-pyrrolidinemethanol
N-Methyl-D-prolinol
CAS: 99494-01-6
Molecular Formula: C6H13NO
(R)-1-Methyl-2-pyrrolidinemethanol - Names and Identifiers
(R)-1-Methyl-2-pyrrolidinemethanol - Physico-chemical Properties
| Molecular Formula | C6H13NO |
| Molar Mass | 115.17 |
| Density | 0.971 g/mL at 25 °C |
| Boling Point | 68-71°C(lit.) |
| Flash Point | 71℃ |
| pKa | 14.77±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | n20/D4.469 |
(R)-1-Methyl-2-pyrrolidinemethanol - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. |
| UN IDs | NA 1993 / PGIII |
| WGK Germany | 3 |
(R)-1-Methyl-2-pyrrolidinemethanol - Introduction
N-Methyl-D-prolinol(N-Methyl-D-prolinol) is an organic compound with the chemical formula C8H17NO2. It is a white crystalline solid, soluble in water and common organic solvents at room temperature.
N-Methyl-D-prolinol has chirality and is an optically active compound. Its chiral center is located on the carbon atom of prolinol, so there are D and L isomers. In pharmaceutical research, this compound is often used in the synthesis of chiral drugs and organic catalysts.
N-Methyl-D-prolinol has a wide range of applications in organic synthesis. It can play an important role as a chiral inducer in asymmetric catalytic reactions and can be used to prepare chiral organic molecules. In addition, it can also be used as an important intermediate in drug synthesis, for the synthesis of anti-cancer drugs, antibiotics and so on.
The preparation methods of N-Methyl-D-prolinol mainly include chemical synthesis and microbial fermentation. Chemical synthesis can be obtained by methylation of prolinol, while microbial fermentation is synthesized by the action of microbial enzymes.
Regarding safety information, N-Methyl-D-prolinol there are no obvious safety issues under general conditions of use, as a chemical substance, the following points still need to be paid attention to: First, avoid inhaling dust or vapor and avoid direct contact with skin and eyes. Second, store in a cool and dry place, away from fire and flammable materials. Finally, wear appropriate protective equipment such as gloves and safety glasses when using.
N-Methyl-D-prolinol has chirality and is an optically active compound. Its chiral center is located on the carbon atom of prolinol, so there are D and L isomers. In pharmaceutical research, this compound is often used in the synthesis of chiral drugs and organic catalysts.
N-Methyl-D-prolinol has a wide range of applications in organic synthesis. It can play an important role as a chiral inducer in asymmetric catalytic reactions and can be used to prepare chiral organic molecules. In addition, it can also be used as an important intermediate in drug synthesis, for the synthesis of anti-cancer drugs, antibiotics and so on.
The preparation methods of N-Methyl-D-prolinol mainly include chemical synthesis and microbial fermentation. Chemical synthesis can be obtained by methylation of prolinol, while microbial fermentation is synthesized by the action of microbial enzymes.
Regarding safety information, N-Methyl-D-prolinol there are no obvious safety issues under general conditions of use, as a chemical substance, the following points still need to be paid attention to: First, avoid inhaling dust or vapor and avoid direct contact with skin and eyes. Second, store in a cool and dry place, away from fire and flammable materials. Finally, wear appropriate protective equipment such as gloves and safety glasses when using.
Last Update：2024-04-09 21:00:56
