(R)-1-N-BOC-哌啶-2-乙醇

(R)-1-N-BOC-哌啶-2-乙醇 - Names and Identifiers

Name	tert-butyl (2R)-2-(2-hydroxyethyl)piperidine-1-carboxylate
Synonyms	(R)-1-N-BOC-PIPERIDINE-2-ETHANOL (R)-1-N-Boc-piperidine-2-ethanol (R)-tert-Butyl2-(2-hydroxyethyl)piperidine-1-carboxylate tert-Butyl (2R)-2-(2-hydroxyethyl)piperidine-1-carboxylate tert-butyl (2R)-2-(2-hydroxyethyl)piperidine-1-carboxylate 1-Piperidinecarboxylic acid, 2-(2-hydroxyethyl)-, 1,1-dimethylethyl ester, (2R)- 1-Piperidinecarboxylic acid, 2-(2-hydroxyethyl)-, 1,1-dimethylethyl ester, (2R)-
CAS	250249-85-5
InChI	InChI=1/C12H23NO3/c1-12(2,3)16-11(15)13-8-5-4-6-10(13)7-9-14/h10,14H,4-9H2,1-3H3/t10-/m1/s1

(R)-1-N-BOC-哌啶-2-乙醇 - Physico-chemical Properties

Molecular Formula	C12H23NO3
Molar Mass	229.32
Density	1.043
Boling Point	324.1±15.0 °C(Predicted)
Flash Point	149.8°C
Vapor Presure	1.97E-05mmHg at 25°C
pKa	15.15±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.478

(R)-1-N-BOC-哌啶-2-乙醇 - Introduction

tert-butyl (2R)-2-(2-hydroxyethyl)piperidine-1-carboxylate, also known as tert-butyl (2R)-2-(2-hydroxyethyl)piperidine-1-carboxylate, is an organic compound. The following is an introduction to its nature, use, preparation and safety information:

Nature:
-Appearance: Usually white crystals or solid powder.
-molecular formula: C14H25NO3.
-Molecular weight: 259.35g/mol.
-Melting point: About 60-65 degrees Celsius.
-Solubility: Soluble in common organic solvents such as ethanol, chloroform and dichloromethane.

Use:
- tert-butyl (2R)-2-(2-hydroxyethyl)piperidine-1-carboxylate as a chiral intermediate, commonly used in organic synthesis reactions.
-It can be used as an important raw material for the synthesis of drugs, pesticides, cosmetics and other organic compounds.

Method:
-A common preparation method is obtained by reacting N-Boc-piperidine with 2-chloroethanol. tert-butyl (2R)-2-(2-hydroxyethyl)piperidine-1-carboxylate.

Safety Information:
- tert-butyl (2R)-2-(2-hydroxyethyl)piperidine-1-carboxylate are generally relatively safe under correct operation. However, it is still an organic compound, and the following points should be noted:
-It may be irritating to the eyes, skin and respiratory tract and direct contact should be avoided.
-Use with appropriate protective equipment, such as laboratory gloves and goggles.
-Avoid ignition and contact with strong oxidants during handling and storage.

Last Update：2024-04-09 20:45:29