(R)-2,3-Dihydro-1H-inden-1-amine

(R)-2,3-Dihydro-1H-inden-1-amine - Names and Identifiers

Name	(R)-(-)-1-Aminoindan
Synonyms	(R)-1-AMINOINDAN (R)-1-AMINOINDANE (R)-(-)-INDANAMINE R-(-)-1-aminoindan (R)-INDAN-1-YLAMINE (R)-(-)-1-INDANAMINE (R)-(-)-1-Aminoindan (R)-(-)-1-AMINOINDAN (R)-(-)-1-AMINOINDANE (R)-2,3-DIHYDRO-1H-INDEN-1-AMINE (1R)-2,3-dihydro-1H-inden-1-amine (1S)-2,3-dihydro-1H-inden-1-amine
CAS	10277-74-4
EINECS	626-982-6
InChI	InChI=1/C9H11N/c10-9-6-5-7-3-1-2-4-8(7)9/h1-4,9H,5-6,10H2/t9-/m0/s1

(R)-2,3-Dihydro-1H-inden-1-amine - Physico-chemical Properties

Molecular Formula	C9H11N
Molar Mass	133.19
Density	1.038 g/mL at 25 °C (lit.)
Melting Point	15 °C (lit.)
Boling Point	96-97 °C/8 mmHg (lit.)
Specific Rotation(α)	-20 º (C=1.5, MEOH)
Flash Point	202°F
Water Solubility	Soluble in methanol. Not miscible or difficult to mix in water.
Vapor Presure	0.0886mmHg at 25°C
BRN	3196204
pKa	9.44±0.20(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,2-8°C
Sensitive	Air Sensitive
Refractive Index	n20/D 1.562
MDL	MFCD00216669
Physical and Chemical Properties	Storage Conditions: 2-8℃ sensitivity: Air Sensitive WGK Germany:3

(R)-2,3-Dihydro-1H-inden-1-amine - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection S61 - Avoid release to the environment. Refer to special instructions / safety data sheets.
UN IDs	UN 3082 9 / PGIII
WGK Germany	3
FLUKA BRAND F CODES	10-34
HS Code	29214990

(R)-2,3-Dihydro-1H-inden-1-amine - Introduction

(R)-(-)-1-aminoindane is a chiral compound with the chemical formula C9H9N. It is a white crystal or crystalline powder, soluble in highly polar solvents such as alcohols, ketones and ethers, and insoluble in non-polar solvents such as benzene and petroleum ether.

The main use of (R)-(-)-1-aminoindan is as a precursor for chiral auxiliaries and catalysts. It is widely used in organic synthesis, especially in the field of asymmetric synthesis. Because of its chirality, it can produce enantiomers and can be used to synthesize chiral compounds.

There are two main methods for preparing (R)-(-)-1-aminoindane. One is the method of chiral resolution of (±)-1-aminoindane, such as enantiomer crystallization separation, chiral fluorescent labeling, etc., to obtain a single chiral product. The other is the selective synthesis of (R)-(-)-1-aminoindane by using chiral catalysts to catalyze the asymmetric reduction.

Regarding the safety information of (R)-(-)-1-aminoindan, it is an organic compound, so you need to pay attention to its correct handling and storage. When using, should follow the laboratory safety procedures, avoid contact with skin, eyes and inhalation of particles. Exposure in the body may cause irritation and allergic reactions. Therefore, appropriate personal protective equipment such as gloves and goggles should be used. In addition, it should be stored in a closed container, away from fire and oxidizing agents. If necessary, a chemical professional should be consulted for more detailed safety information.

Last Update：2024-04-10 22:29:15