(R)-2-(2-(Diphenylphosphino)phenyl)-4,5-dihydro-4-phenyloxazole - Names and Identifiers
(R)-2-(2-(Diphenylphosphino)phenyl)-4,5-dihydro-4-phenyloxazole - Physico-chemical Properties
Molecular Formula | C27H22NOP
|
Molar Mass | 407.451 |
Boling Point | 555.7±50.0 °C(Predicted) |
pKa | 3.60±0.70(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
(R)-2-(2-(Diphenylphosphino)phenyl)-4,5-dihydro-4-phenyloxazole - Risk and Safety
Safety Description | 24/25 - Avoid contact with skin and eyes.
|
WGK Germany | 3 |
FLUKA BRAND F CODES | 10-23 |
HS Code | 29349990 |
(R)-2-(2-(Diphenylphosphino)phenyl)-4,5-dihydro-4-phenyloxazole - Introduction
R(-)-2-(2-(DIPHENYLPHOSPHINO)PHENYL)-(R(-)-2-(2-(diphenylphosphino)phenyl)-) it is a chiral organic compound. Its main properties are as follows:
1. Appearance: white solid.
2. Molecular formula: C26H20NOPS.
3. Molecular weight: 415.47g/mol.
4. Melting point: about 130-135 ° C.
5. Optical rotation:[α]D ^ 20=-48 °.
6. Solubility: Soluble in organic solvents.
The main use of this compound is as a chiral ligand for catalytic asymmetric synthesis reactions. It can form coordination complexes with transition metals and participate in asymmetric hydrogenation, Hydride Transfer and asymmetric carbonyl reactions.
In terms of preparation, R(-)-2-(2-(DIPHENYLPHOSPHINO)PHENYL)-can be synthesized through the following steps-:
1. First, phenyl magnesium bromide reacts with diphenyl phosphine to generate diphenyl phosphine phenyl magnesium bromide.
2. Then, it is reacted with 2-bromophenyl oxazoline to obtain R(-)-2-(2-(DIPHENYLPHOSPHINO)PHENYL)-.
When using and handling this compound, you need to pay attention to the following safety information:
1. The compound may be irritating to the skin and eyes, and direct contact should be avoided.
2. During the operation should wear appropriate protective measures, such as laboratory gloves, goggles and laboratory coat.
3. Should be used in a well-ventilated environment, avoid inhaling its dust or vapor.
4. Avoid contact with oxidants and strong acids/bases to avoid dangerous reactions.
5. The use and handling of the compound should be carried out under the guidance of professionals.
Last Update:2024-04-10 22:29:15