(R)-2-Boc-Amino-Γ-Butyrolactone

(R)-2-Boc-Amino-Γ-Butyrolactone - Names and Identifiers

Name	Boc-D-homoserine lactone
Synonyms	Boc-dHsl Boc-D-HoMoser lactone Boc-D-homoserine lactone (R)-2-Boc-Amino-Γ-Butyrolactone (R)-2- BOC-AMINO -γ-BUTYROLACTONE (R)-2- Boc-AMino -γ-ButyrolaCLone (R)-(-)-Alpha-(Boc-Amino)-Gamma-Butyrolactone (R)-tert-butyl 2-oxo-tetrahydrofuran-3-ylcarbamate tert-Butyl N-[(3R)-2-oxotetrahydrofuran-3-yl]carbamate
CAS	67198-86-1

(R)-2-Boc-Amino-Γ-Butyrolactone - Physico-chemical Properties

Molecular Formula	C9H15NO4
Molar Mass	201.22
Density	1.15±0.1 g/cm3(Predicted)
Melting Point	115-118 °C(Solv: dichloromethane (75-09-2); methanol (67-56-1))
Boling Point	363.7±31.0 °C(Predicted)
Appearance	Transparent liquid
pKa	11.21±0.20(Predicted)
Storage Condition	2-8°C

(R)-2-Boc-Amino-Γ-Butyrolactone - Introduction

Boc-D-homoserine lactone, also known as Boc-D-homoserine lactone, is an organic compound. Its chemical structure contains a 2-oxotetrahydrofuran-3-yl ring and a tert-butyl carbamate functional group attached to the ring.

The nature of the Boc-D-homoserine lactone is as follows:
-Appearance: Colorless to light yellow solid
-Molecular formula: C11H19NO4
-Molecular weight: 233.27g/mol
-Solubility: Soluble in common organic solvents such as ethanol and dimethylformamide

Boc-D-homoserine lactone are mainly used as intermediates in organic synthesis. It can be used for the synthesis of polypeptides and low molecular compounds. In addition, it is also widely used in life science research, such as drug development and biomedical research.

The method of preparing Boc-D-homoserine lactone can be achieved by chemical synthesis. A common method is the esterification of 2-oxotetrahydrofuran-3-yl carboxylic acid with tert-butanol, followed by esterification with carbamic acid and diethylcarbamide to obtain the Boc-D-homoserine lactone.

With regard to safety information, the toxicological nature of Boc-D-homoserine lactone is unclear due to insufficient relevant data. However, attention should be paid to possible hazards based on routine laboratory operations and general hazardous material handling procedures. Appropriate personal protective measures, such as gloves, glasses and laboratory coats, should be taken when using or handling Boc-D-homoserine lactone. Safety procedures for the use and handling of chemicals must be followed to ensure safety.

Last Update：2024-04-09 21:04:16