(R)-2-哌啶-氨甲基甲酸叔丁酯
(R)-Piperidin-2-Ylmethyl-Carbamic Acid Tert-Butyl Ester
CAS: 139004-96-9;139004-93-6
Molecular Formula: C11H22N2O2
(R)-2-哌啶-氨甲基甲酸叔丁酯 - Names and Identifiers
(R)-2-哌啶-氨甲基甲酸叔丁酯 - Physico-chemical Properties
| Molecular Formula | C11H22N2O2 |
| Molar Mass | 214.3 |
| Density | 1.01g/cm3 |
| Boling Point | 287.9°C at 760 mmHg |
| Flash Point | 127.9°C |
| Vapor Presure | 0.00242mmHg at 25°C |
| Appearance | solid |
| Storage Condition | 2-8°C |
| Refractive Index | 1.485 |
(R)-2-哌啶-氨甲基甲酸叔丁酯 - Introduction
(S)-tert-butyl (piperidin-2-ylmethyl) carbamate, also known as (S)-tert-butyl(2-piperidylmethyl)carbamate. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
1. appearance: usually white crystal or solid.
2. Melting point: about 67-71°C.
3. molecular formula: C12H23NO2.
4. Molecular weight: 209.32g/mol.
5. solubility: soluble in some organic solvents, such as chloroform, ether, acetonitrile, insoluble in water.
Use:
(S)-tert-butyl (piperidin-2-ylmethyl) carbamate is a chiral reagent commonly used in organic synthesis, which is often used in catalytic reaction and chiral separation in asymmetric synthesis. It can be used as chiral derivatizing agent, catalyst and chiral catalyst etc. Specific applications include drug synthesis, pesticide synthesis, hormone synthesis, etc.
Preparation Method:
The preparation of (S)-tert-butyl (piperidin-2-ylmethyl) carbamate can be carried out by the following method:
1. First, (S)-( )-α-piperidinethoxymethanol and (S)-tert-butylaminazepine were dissolved in dichloromethane, respectively.
2. Then, mix the two solutions, add excess dihydroxyethyl dichloroformate, and the reaction proceeds for a longer time.
3. Finally, an ether solvent was added and distilled to obtain (S)-tert-butyl (piperidin-2-ylmethyl) carbamate.
Safety Information:
1. As a chemical, you need to pay attention to protective measures when using, such as wearing protective gloves and glasses.
2. avoid contact with skin, eyes and mucous membranes, such as accidental contact, should immediately rinse with plenty of water, and seek medical help.
3. in the operation, should avoid the inhalation of dust or steam. Use a protective mask if necessary.
4. The compound should be stored in a dry, dark place, away from fire and oxidant.
Please note that this information is for reference only. Please follow relevant safety procedures and regulations when using this compound.
Nature:
1. appearance: usually white crystal or solid.
2. Melting point: about 67-71°C.
3. molecular formula: C12H23NO2.
4. Molecular weight: 209.32g/mol.
5. solubility: soluble in some organic solvents, such as chloroform, ether, acetonitrile, insoluble in water.
Use:
(S)-tert-butyl (piperidin-2-ylmethyl) carbamate is a chiral reagent commonly used in organic synthesis, which is often used in catalytic reaction and chiral separation in asymmetric synthesis. It can be used as chiral derivatizing agent, catalyst and chiral catalyst etc. Specific applications include drug synthesis, pesticide synthesis, hormone synthesis, etc.
Preparation Method:
The preparation of (S)-tert-butyl (piperidin-2-ylmethyl) carbamate can be carried out by the following method:
1. First, (S)-( )-α-piperidinethoxymethanol and (S)-tert-butylaminazepine were dissolved in dichloromethane, respectively.
2. Then, mix the two solutions, add excess dihydroxyethyl dichloroformate, and the reaction proceeds for a longer time.
3. Finally, an ether solvent was added and distilled to obtain (S)-tert-butyl (piperidin-2-ylmethyl) carbamate.
Safety Information:
1. As a chemical, you need to pay attention to protective measures when using, such as wearing protective gloves and glasses.
2. avoid contact with skin, eyes and mucous membranes, such as accidental contact, should immediately rinse with plenty of water, and seek medical help.
3. in the operation, should avoid the inhalation of dust or steam. Use a protective mask if necessary.
4. The compound should be stored in a dry, dark place, away from fire and oxidant.
Please note that this information is for reference only. Please follow relevant safety procedures and regulations when using this compound.
Last Update：2024-04-09 21:01:54
Supplier List
Multiple Specifications
Product Name: (R)-PIPERIDIN-2-YLMETHYL-CARBAMIC ACID TERT-BUTYL ESTER Visit Supplier Webpage Request for quotationCAS: 139004-93-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Multiple Specifications
Product Name: (R)-PIPERIDIN-2-YLMETHYL-CARBAMIC ACID TERT-BUTYL ESTER Visit Supplier Webpage Request for quotationCAS: 139004-93-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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