(R)-3-Methylmorpholine - Names and Identifiers
(R)-3-Methylmorpholine - Physico-chemical Properties
Molecular Formula | C5H11NO
|
Molar Mass | 101.15 |
Density | 0.891±0.06 g/cm3(Predicted) |
Boling Point | 137.1±15.0 °C(Predicted) |
Flash Point | 41.3°C |
Vapor Presure | 7.14mmHg at 25°C |
pKa | 9.03±0.40(Predicted) |
Storage Condition | 2-8°C(protect from light) |
Refractive Index | 1.409 |
(R)-3-Methylmorpholine - Introduction
(3R)-3-methylmorpholine is an organic compound with the chemical formula C5H11NO. It is a colorless liquid with a special pungent odor. The following is a description of the properties, uses, preparation and safety information of (3R)-3-methylmorpholine:
Nature:
1. (3R)-3-methylmorpholine is a chiral molecule with two enantiomers:(3R)-3-methylmorpholine and (S)-3-methylmorpholine.
2. It is a water-soluble liquid with low volatility at room temperature.
3. (3R)-3-methylmorpholine is alkaline and can be neutralized with acid under acidic conditions.
4. It is a stable compound that is not easy to decompose or chemically react under conventional storage conditions.
Use:
1. (3R)-3-methylmorpholine is commonly used as a catalyst or reagent and is widely used in organic synthesis.
2. It can be used to synthesize organic compounds with pharmaceutical activity, such as the preparation of certain pharmaceutical intermediates.
3. It can also be used to prepare various chemicals, such as surfactants, dyes, pesticides, etc.
Preparation Method:
(3R)-3-methylmorpholine has many preparation methods, and the commonly used methods include the following:
1. (3R)-3-methylmorpholine was obtained by the reaction of morpholine and methyl magnesium bromide.
2. through the reaction of morpholine and methyl ethyl ketone, and then reduced to obtain (3R)-3-methylmorpholine.
3. (3R)-3-methylmorpholine was obtained by chiral resolution using (S)-3-methylmorpholine.
Safety Information:
1. (3R)-3-methylmorpholine is an irritant compound that may cause irritation and discomfort in contact with the skin, eyes, or respiratory tract.
2. Wear appropriate protective equipment such as gloves, goggles and respiratory protection during use.
3. avoid contact with strong oxidants, strong acids or strong bases to avoid dangerous reactions.
4. in the storage process should avoid high temperature and fire, maintain good ventilation storage conditions.
5. When handling (3R)-3-methylmorpholine, the relevant safety procedures should be followed, and contact and inhalation should be strictly controlled.
Last Update:2024-04-09 02:00:48