(R)-6-(3-((3-Hydroxy-1-methyl-2-oxopyrrolidin-3-yl)ethynyl)phenyl)-4-methoxypicolinamide
NIK SMI1
CAS: 1660114-31-7
Molecular Formula: C20H19N3O4
(R)-6-(3-((3-Hydroxy-1-methyl-2-oxopyrrolidin-3-yl)ethynyl)phenyl)-4-methoxypicolinamide - Names and Identifiers
(R)-6-(3-((3-Hydroxy-1-methyl-2-oxopyrrolidin-3-yl)ethynyl)phenyl)-4-methoxypicolinamide - Physico-chemical Properties
| Molecular Formula | C20H19N3O4 |
| Molar Mass | 365.38 |
| Density | 1.39±0.1 g/cm3(Predicted) |
| Boling Point | 626.7±55.0 °C(Predicted) |
| pKa | 11.14±0.20(Predicted) |
| Storage Condition | 2-8℃ |
(R)-6-(3-((3-Hydroxy-1-methyl-2-oxopyrrolidin-3-yl)ethynyl)phenyl)-4-methoxypicolinamide - Reference Information
| biological activity | NIK SMI1 is an efficient and selective inhibitor of NF-κB-inducting kinase (NIK) with a Ki value of 0.23 nM and can be used for NIK to catalyze ATP hydrolysis to ADP. |
| target | TargetValue NIK-catalyzed hydrolysis of ATP to ADP () 0.23 nM(Ki) |
| Target | Value |
| NIK-catalyzed hydrolysis of ATP to ADP () | 0.23 nM(Ki) |
Last Update：2024-04-10 22:29:15
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