(R)-MOP

(R)-MOP - Names and Identifiers

Name	(R)-2-(diphenylphosphino)-2'-methoxy-1,1'-binaphthyl (R)-MOP
Synonyms	(R)-MOP (R)-(+)-MOP (S)-2-diphenyphosphino,2'-methoxyl-1,1'-binaphthyl (S)-2-(DIPHENYLPHOSPHINO)-2'-METHOXY-1,1'-BINAPHTHYL (R)-(+)-2-DIPHENYLPHOSPHINO-2'-METHOXY-1,1'-BINAPHTHYL (S)-(-)-(DIPHENYLPHOSPHINO)-2'-METHOXY-1,1'-BINAPHTHYL (2'-methoxy-1,1'-binaphthalen-2-yl)(diphenyl)phosphane (S)-(-)-2-(DIPHENYLPHOSPHINO)-2'-METHOXY-1,1'-BINAPHTHYL (R)-(+)-2-(Diphenylphosphino)-2'-methoxy-1,1'-binaphthyl (R)-(2'-Methoxy[1,1'-binaphthalen]-2-yl)diphenyl-phosphine (R)-2-(diphenylphosphino)-2'-methoxy-1,1'-binaphthyl (R)-MOP
CAS	145964-33-6 134484-37-0
InChI	InChI=1/C33H25OP/c1-34-30-22-20-24-12-8-10-18-28(24)32(30)33-29-19-11-9-13-25(29)21-23-31(33)35(26-14-4-2-5-15-26)27-16-6-3-7-17-27/h2-23H,1H3

(R)-MOP - Physico-chemical Properties

Molecular Formula	C33H25OP
Molar Mass	468.52
Melting Point	177-179°C
Boling Point	584.1±38.0 °C(Predicted)
Specific Rotation(α)	+67° ±2° (c 1, toluene)
Flash Point	386.1°C
Solubility	almost transparency in Toluene
Vapor Presure	5.09E-13mmHg at 25°C
Appearance	Powder
Color	white
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Sensitive	air sensitive
MDL	MFCD00269686

(R)-MOP - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany	3

(R)-MOP - Introduction

(R)-2-(diphenylphosphino)-2 '-methoxy-1,1'-binaphthyl (R)-MOP, also known as (R)-BINAP, is a chiral organic molecule. Its chemical name is (1R,2R)-(-)-1,1 '-binaphthyl-2',2 "-Dibis (diphenylphosphine), and its chemical formula is C44H30OP2.

(R)-BINAP has many useful properties, including excellent solubility, thermal stability, and acid-base stability. It is a colorless crystalline solid, soluble in many organic solvents, such as ethanol, dimethylformamide and dichloromethane. It also has high optical rotation and the ability to recognize heavy metal ions.

(R)-BINAP has a wide range of applications in organic synthesis and metal-catalyzed reactions. It is often used as a chiral ligand and acts as a catalyst in asymmetric synthesis. It can form stable complexes with transition metals and catalyze various organic synthesis reactions, such as asymmetric hydrogenation, diazotization and catalytic reduction. In addition,(R)-BINAP can also be used in drug synthesis, materials science and biochemistry.

The method of preparing (R)-BINAP is relatively simple. A common preparation method is to synthesize it by an intramolecular substitution reaction, usually using binaphthyl and diphenylphosphine as starting materials, and the reaction is carried out in the presence of basic conditions. There are other methods, such as preparation using ligand exchange reactions or metal catalyzed reactions.

When using and handling (R)-BINAP, pay attention to safety and operating specifications. It is a chemical that can be harmful to humans and the environment. Appropriate protective equipment should be worn to avoid contact with skin and eyes. Follow proper laboratory procedures and regulations for waste disposal. In addition, it should be stored in a dry, cool and well-ventilated place, avoiding contact with oxygen, strong oxidants, acids and high temperatures.

Last Update：2024-04-09 20:52:54