(R)-MethylN-tert-butoxycarbonylMorpholine-3-carboxylate

(R)-MethylN-tert-butoxycarbonylMorpholine-3-carboxylate - Names and Identifiers

Name	(S)-4-tert-butyl 3-Methyl Morpholine-3,4-dicarboxylate
Synonyms	METHYL (S)-4-BOC-MORPHOLINE-3-CARBOXYLATE 3-(S)-Methoxycarbonyl-4-tbutoxycarbonylMorpholine (S)-tert-butyl methyl morpholine-3,4-dicarboxylate (S)-4-tert-butyl 3-Methyl Morpholine-3,4-dicarboxylate 4-(tert-butyl)3-methyl(S)-morpholine-3,4-dicarboxylate (R)-MethylN-tert-butoxycarbonylMorpholine-3-carboxylate (S)-4-(tert-butoxycarbonyl)-3-MethylMorpholine-3-carboxylic acid (3S)-3,4-Morpholinedicarboxylic acid 4-(1,1-dimethylethyl) 3-methyl ester
CAS	215917-98-9

(R)-MethylN-tert-butoxycarbonylMorpholine-3-carboxylate - Physico-chemical Properties

Molecular Formula	C11H19NO5
Molar Mass	245.27
Storage Condition	2-8°C

(R)-MethylN-tert-butoxycarbonylMorpholine-3-carboxylate - Introduction

(S)-4-tert-butyl 3-Methyl Morpholine-3,4-dicarboxylate, also known as (S)-4-tert-butyl 3-Methyl Morpholine-3,4-dicarboxylate, is an organic compound.

The properties of the compound are as follows:

Appearance: Colorless to light yellow solid
Molecular formula: C13H23NO5
Molecular weight: 281.32g/mol
Melting point: 68-70 ° C
Boiling point: 293-295 ° C
Solubility: Soluble in common organic solvents, such as ethanol, dimethyl alkane and chloroform.

The main uses of this compound are as follows:

1. As an intermediate in organic synthesis, used in the synthesis of other compounds;
2. As a raw material in drug synthesis, it plays an important role in drug research and development.

The method for preparing (S)-4-tert-butyl 3-Methyl Morpholine-3,4-dicarboxylate is as follows:

This compound can be obtained by reacting 3-methylmorpholine with (Boc)2O. The specific steps are as follows:
1.3-methyl morpholine is dissolved in dry dimethylalkylene, and triethylamine is added as a catalyst.
2. Slowly add (Boc)2O to the solution and keep the reaction temperature below 5°C.
3. After completion of the reaction, the product was extracted using an ether solvent.
4. The product was purified by crystallization or column chromatography.

For safety information,(S)-4-tert-butyl 3-Methyl Morpholine-3, the specific provisions of 4-dicarboxylate need to refer to the relevant chemical safety data sheet. Generally speaking, chemicals should be used in accordance with laboratory operating procedures, and strictly follow relevant safe operating procedures and personal protective measures. Wear appropriate protective gloves, glasses and protective clothing when handling the compound, and ensure that the operation is carried out in a well-ventilated area.

Last Update：2024-04-09 20:02:46